Effectiveness of a targeted lifestyle intervention in primary care on diet and physical activity among South Asians at risk for diabetes: 2-year results of a randomised controlled trial in the Netherlands.

In South Asian populations, little is known about the effects of intensive interventions to reduce the risk of type 2 diabetes on health behaviour. We examined the effectiveness at 2 years of a culturally targeted lifestyle intervention on diet, physical activity and determinants of behaviour change among South Asians at risk for diabetes. Randomised controlled trial with de facto masking. Primary care. A total of 536 18- to 60-year-old South Asians at risk for diabetes (ie, with impaired glucose tolerance, impaired fasting glucose or relatively high insulin resistance) were randomised to the intervention (n=283) or a control (n=253) group. Data of 314 participants (n=165 intervention, n=149 control) were analysed. The culturally targeted intervention consisted of individual counselling using motivational interviewing (six to eight sessions in the first 6 months plus three to four booster sessions), a family session, cooking classes and a supervised physical activity programme. The control group received generic lifestyle advice. We compared changes in physical activity, diet and social-cognitive underlying determinants between the two groups at 2-year follow-up with independent-sample t-tests, chi-square tests and Fisher's exact tests. At the 2-year follow-up, participants in the intervention group were more moderately to vigorously active than at baseline, but compared with changes in the control group, the difference was not significant (change min/week 142.9 vs 0.5, p=0.672). Also, no significant difference was found between the two groups in changes on any of the components of the diet or the social-cognitive determinants of diet and physical activity. The culturally targeted lifestyle intervention led to high drop-out and was not effective in promoting healthy behaviour among South Asians at risk for diabetes. Given the high a priori risk, we recommend to develop new strategies, preferably more acceptable, to promote healthy behaviour. NTR1499; Results. www.trialregister.nl/trialreg/admin/rctview.asp?TC=1499.

Vlaar EMA ，Nierkens V ，Nicolaou M ，Middelkoop BJC ，Busschers WB ，Stronks K ，van Valkengoed IGM ... -  《BMJ Open》

Feasibility and effectiveness of a targeted diabetes prevention program for 18 to 60-year-old South Asian migrants: design and methods of the DH!AAN study.

Vlaar EM ，van Valkengoed IG ，Nierkens V ，Nicolaou M ，Middelkoop BJ ，Stronks K ... -  《-》

An evaluation of the DEXLIFE 'self-selected' lifestyle intervention aimed at improving insulin sensitivity in people at risk of developing type 2 diabetes: study protocol for a randomised controlled trial.

O'Donoghue GM ，Kennedy A ，Andersen GS ，Durkan E ，Thybo T ，Sinnott M ，Nolan JJ ，O'Gorman DJ ... -  《Trials》

Intensive lifestyle intervention in general practice to prevent type 2 diabetes among 18 to 60-year-old South Asians: 1-year effects on the weight status and metabolic profile of participants in a randomized controlled trial.

Admiraal WM ，Vlaar EM ，Nierkens V ，Holleman F ，Middelkoop BJ ，Stronks K ，van Valkengoed IG ... -  《-》

Sustained diabetes risk reduction after real life and primary health care setting implementation of the diabetes in Europe prevention using lifestyle, physical activity and nutritional intervention (DE-PLAN) project.

Gilis-Januszewska A ，Lindström J ，Tuomilehto J ，Piwońska-Solska B ，Topór-Mądry R ，Szybiński Z ，Peltonen M ，Schwarz PE ，Windak A ，Hubalewska-Dydejczyk A ... -  《BMC PUBLIC HEALTH》