
自引率: 7.3%
被引量: 35626
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审稿周期: 3.41
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投稿须知/期刊简介:
BMJ Open is an online, open access journal, dedicated to publishing medical research from all disciplines and therapeutic areas. The journal publishes all research study types, from study protocols to phase I trials to meta-analyses, including small, specialist studies, and negative studies. Publishing procedures are built around fully open peer review and continuous publication, publishing research online as soon as the article is ready. <br> BMJ Open aims to promote transparency in the publication process by publishing reviewer reports and previous versions of manuscripts as pre-publication histories. Authors are asked to pay article-publishing charges on acceptance; the ability to pay does not influence editorial decisions. All papers are included in MEDLINE/PubMed and Science Citation Index Expanded (Web of Science). <br> BMJ Open is a medical journal. We consider papers addressing research questions in clinical medicine, public health and epidemiology. We also welcome studies in health services research, health economics, surgery, qualitative research, research methods, medical education, medical publishing and any other field that directly addresses patient outcomes or the practice and delivery of healthcare. Our focus is on research that is relevant to patients and clinicians. We do not publish studies conducted in animals, laboratory studies not linked to patient outcomes, papers reporting solely physiological or biomechanical results from healthy participants, anatomy, cell biology or non-clinical psychology. All research study types are considered, from study protocols through phase I trials to meta-analyses. This includes specialist studies and studies reporting negative results. Case reports should be submitted to BMJ Case Reports. BMJ Open 是世界最大的临床综合医学期刊 范围:BMJ Open接收临床医学、公共卫生和流行病学的研究文章。同时,欢迎来自以下领域的研究投稿:卫生服务研究、卫生经济学、外科、定性研究、研究方法、医学教育、医学出版以及其它与影响患者健康的因素或医疗实践直接相关的研究。 BMJ Open关注的是与患者和临床医生相关的研究,不考虑动物研究、与患者健康不相关的实验室研究、仅从健康人群得出的生理学或生物力学结果、解剖学、细胞生物学以及非临床心理学。 研究类型:从研究方案到一期临床试验再到荟萃分析的所有研究类型都会考虑,包括专科研究。阴性结果的研究也欢迎投稿。病例报告请投至BMJ CaseReports。 初衷:BMJOpen的出版目的是为了给所有恰当执行的医学研究提供一个严格且透明的同行评审出版平台。为了提高被接收的几率,请访问作者指南和作者资源网页来指导您的写作、完善您的投稿。 质效:BMJOpen致力于实现快速的出版流程、全透明的同行评审过程和不间断的更新。为了提高评审透明度,审稿人意见与稿件所有版本都会作为出版历史同文章的最终版本一并发表。 收费:作者在文章被接收后,需要支付开放获取文章处理费用。付款能力不会影响编辑的决定。费率为研究文章1350英镑,研究方案1000英镑。 投稿信息 ● 开放获取类型:完全开放获取<br> ● 收稿率:55%<br> ● 出版频率:不间断出版<br> ● 出版速度:投稿至初步决定:平均50天<br> ● 开放获取文章处理费:<br> 研究文章:英镑£1350,美元$2200,欧元€1900;<br> Protocol文章:英镑£1000,美元$1650,欧元€1450<br> ● 被索引情况:Science Citation Index Expanded (Web of Science), PubMed, PubMed Central, Medline, Scopus, Google Scholar, CAB Abstracts, Global Health (CABI)<br> ● 创刊时间:2011年 BMJ旗下更多优质期刊 Gut<br> Annals of the Rheumatic Diseases<br> Thorax<br> British Journal of Sports Medicine<br> Tobacco Control<br> Journal of Medical Genetics<br> bmj quality & safety
期刊描述简介:
BMJ Open is an online, open access journal, dedicated to publishing medical research from all disciplines and therapeutic areas. The journal publishes all research study types, from study protocols to phase I trials to meta-analyses, including small, specialist studies, and negative studies. Publishing procedures are built around fully open peer review and continuous publication, publishing research online as soon as the article is ready. BMJ Open aims to promote transparency in the publication process by publishing reviewer reports and previous versions of manuscripts as pre-publication histories. Authors are asked to pay article-publishing charges on acceptance; the ability to pay does not influence editorial decisions. All papers are included in MEDLINE/PubMed and Science Citation Index Expanded (Web of Science). BMJ Open is a medical journal. We consider papers addressing research questions in clinical medicine, public health and epidemiology. We also welcome studies in health services research, health economics, surgery, qualitative research, research methods, medical education, medical publishing and any other field that directly addresses patient outcomes or the practice and delivery of healthcare. Our focus is on research that is relevant to patients and clinicians. We do not publish studies conducted in animals, laboratory studies not linked to patient outcomes, papers reporting solely physiological or biomechanical results from healthy participants, anatomy, cell biology or non-clinical psychology. All research study types are considered, from study protocols through phase I trials to meta-analyses. This includes specialist studies and studies reporting negative results. Case reports should be submitted to BMJ Case Reports.
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Correlation of the treatment sensitivity of patient-derived organoids with treatment outcomes in patients with head and neck cancer (SOTO): protocol for a prospective observational study.
Organoids have been successfully used in several areas of cancer research and large living biobanks of patient-derived organoids (PDOs) have been developed from various malignancies. The characteristics of the original tumour tissue such as mutation signatures, phenotype and genetic diversity are well preserved in organoids, thus showing promising results for the use of this model in translational research. In this study, we aim to assess whether we can generate PDOs from head and neck squamous cell carcinoma (HNSCC) samples and whether PDOs can be used to predict treatment sensitivity in HNSCC patients as well as to explore potential biomarkers. This is a prospective observational study at a single centre (Guy's and St Thomas' NHS Foundation Trust) to generate PDOs from patients' samples to assess treatment response and to correlate with patients' treatment outcomes. Patients will be included if they are diagnosed with HNSCC undergoing curative treatment (primary surgery or radiotherapy) or presenting with recurrent or metastatic cancers and they will be categorised into three groups (cohort 1: primary surgery, cohort 2: primary radiotherapy and cohort 3: recurrent/metastatic disease). Research tumour samples will be collected and processed into PDOs and chemosensitivity/radiosensitivity will be assessed using established methods. Moreover, blood and other biological samples (eg, saliva) will be collected at different time intervals during treatment and will be processed in the laboratory for plasma and peripheral blood mononuclear cell (PBMC) isolation. Plasma and saliva will be used for circulating tumour DNA analysis and PBMC will be stored for assessment of the peripheral immune characteristics of the patients as well as to perform co-culture experiments with PDOs. SOTO study (correlation of the treatment Sensitivity of patient-derived Organoids with Treatment Outcomes in patients with head and neck cancer) uses the collaboration of several specialties in head and neck cancer and has the potential to explore multiple areas of research with the aim of offering a valid and effective approach to personalised medicine for cancer patients. This study was approved by North West-Greater Manchester South Research Ethics Committee (REC Ref: 22/NW/0023) on 21 March 2022. An informed consent will be obtained from all participants prior to inclusion in the study. Results will be disseminated via peer-reviewed publications and presentations at international conferences. NCT05400239.
被引量:- 发表:1970
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Incidence and risk factors of common infections among children in Wonago, southern Ethiopia: a prospective cohort study.
被引量:- 发表:1970
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Perceptions of genomic newborn screening: a cross-sectional survey conducted with UK medical students.
被引量:- 发表:1970
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Trends in under-five mortality rate in China, 1996-2020: a Joinpoint regression and correlation analysis.
被引量:- 发表:1970
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What is known about nurse retention in peri-COVID-19 and post-COVID-19 work environments: protocol for a scoping review of factors, strategies and interventions.
被引量:- 发表:1970