Effectiveness of a brief theory-based health promotion intervention among adults at high risk of type 2 diabetes: One-year results from a randomised trial in a community setting.

To examine the effect of a brief theory-based health promotion intervention delivered in the community on health behaviour and diabetes-related risk factors among Danish adults at high risk of diabetes. A randomised trial was conducted among 127 individuals aged 28 to 70 with fasting plasma glucose: 6.1-6.9 mmol/l and/or HbA1c: 6.0-<6.5% (42-<48 mmol/mol) recruited from general practice in Holstebro, Denmark. Participants were randomised to a control group or to receive the intervention delivered over four 2h group sessions during five weeks, and two further sessions after one and six months. Questionnaire data and clinical measures were collected at baseline, three months and one year after intervention. Primary outcomes; total-fat intake <30% of energy intake; saturated-fat intake <10% of energy intake; fibre-intake ≥15 g/1000 kcal; weight reduction >5%; changes in physical activity. 85% attended one-year follow-up. After adjusting for gender, age and education, Odds ratio (OR) (95% CI) intervention vs control: total-fat intake <30% energy intake: 0.52 (0.22;1.20), saturated-fat intake <10% energy intake: 1.22 (0.52;2.87), fibre intake ≥ 15 g/1000 kcal: 1.18 (0.48;2.92), weight reduction >5%: 2.47 (0.95; 6.39). β (95% CI) between intervention vs control in changes from baseline: IPAQ, MET min/week: -236 (-2760; 2288), waist circumference,cm: -2.5 (-4.5; -0.5); systolic blood pressure, mmHg: -4.6 (-8.8; -0.3). A brief theory-based health promotion intervention delivered in the community indicated effect on weight, waist circumference and systolic blood pressure at one year among Danish adults at high risk of diabetes. No effect was shown on diets or physical activity.

Juul L ，Andersen VJ ，Arnoldsen J ，Maindal HT ... -  《-》

An evaluation of the DEXLIFE 'self-selected' lifestyle intervention aimed at improving insulin sensitivity in people at risk of developing type 2 diabetes: study protocol for a randomised controlled trial.

O'Donoghue GM ，Kennedy A ，Andersen GS ，Durkan E ，Thybo T ，Sinnott M ，Nolan JJ ，O'Gorman DJ ... -  《Trials》

Scaling-up from an implementation trial to state-wide coverage: results from the preliminary Melbourne Diabetes Prevention Study.

Janus ED ，Best JD ，Davis-Lameloise N ，Philpot B ，Hernan A ，Bennett CM ，O'Reilly S ，Carter R ，Vartiainen E ，Dunbar JA ，Melbourne Diabetes Prevention Study research group ... -  《-》

Prevention of type 2 diabetes by lifestyle intervention in an Australian primary health care setting: Greater Green Triangle (GGT) Diabetes Prevention Project.

Laatikainen T ，Dunbar JA ，Chapman A ，Kilkkinen A ，Vartiainen E ，Heistaro S ，Philpot B ，Absetz P ，Bunker S ，O'Neil A ，Reddy P ，Best JD ，Janus ED ... -  《BMC PUBLIC HEALTH》

Effectiveness of a targeted lifestyle intervention in primary care on diet and physical activity among South Asians at risk for diabetes: 2-year results of a randomised controlled trial in the Netherlands.

In South Asian populations, little is known about the effects of intensive interventions to reduce the risk of type 2 diabetes on health behaviour. We examined the effectiveness at 2 years of a culturally targeted lifestyle intervention on diet, physical activity and determinants of behaviour change among South Asians at risk for diabetes. Randomised controlled trial with de facto masking. Primary care. A total of 536 18- to 60-year-old South Asians at risk for diabetes (ie, with impaired glucose tolerance, impaired fasting glucose or relatively high insulin resistance) were randomised to the intervention (n=283) or a control (n=253) group. Data of 314 participants (n=165 intervention, n=149 control) were analysed. The culturally targeted intervention consisted of individual counselling using motivational interviewing (six to eight sessions in the first 6 months plus three to four booster sessions), a family session, cooking classes and a supervised physical activity programme. The control group received generic lifestyle advice. We compared changes in physical activity, diet and social-cognitive underlying determinants between the two groups at 2-year follow-up with independent-sample t-tests, chi-square tests and Fisher's exact tests. At the 2-year follow-up, participants in the intervention group were more moderately to vigorously active than at baseline, but compared with changes in the control group, the difference was not significant (change min/week 142.9 vs 0.5, p=0.672). Also, no significant difference was found between the two groups in changes on any of the components of the diet or the social-cognitive determinants of diet and physical activity. The culturally targeted lifestyle intervention led to high drop-out and was not effective in promoting healthy behaviour among South Asians at risk for diabetes. Given the high a priori risk, we recommend to develop new strategies, preferably more acceptable, to promote healthy behaviour. NTR1499; Results. www.trialregister.nl/trialreg/admin/rctview.asp?TC=1499.

Vlaar EMA ，Nierkens V ，Nicolaou M ，Middelkoop BJC ，Busschers WB ，Stronks K ，van Valkengoed IGM ... -  《-》