Negative outcome in cutaneous Mycobacterium marinum infection treated with surgical intervention: Two-case report.

Mycobacterium marinum (M marinum), a slow-growing nontuberculous mycobacterium (NTM), is widely distributed in aquatic environments. It is a well-known cutaneous pathogen, which causes sporotrichosis-like lesions. In this report, we describe 2 cases of subcutaneous M marinum infection. Both patients underwent several surgical procedures at local hospitals, and despite optimal surgical site healing, new lesions appeared in adjacent sites. Based on NTM culture, identification by gene sequencing, and matrix-assisted laser desorption ionization time-of-flight mass spectrometry, the diagnosis of subcutaneous NTM infection was confirmed. The patients were treated with oral rifampicin 0.45 g/day and clarithromycin 1 g/day and oral doxycycline hydrochloride capsules (200 mg/day), respectively. Both patients were treated for 8 and 5 weeks, respectively, and the lesions healed. Surgical debridement cannot compete with or impede NTM lymphatic spread; antimicrobial therapy is the first choice for the treatment of M marinum infections.

Sang B ，Xia X ，Liu Z 《-》

[Skin disease caused by Mycobacterium marinum:a case report].

Song XL ，Xu JG ，Wei YL ，Chen QM ... -  《-》

[Mycobacterium marinum tenosynovitis of the abductors].

Contios S ，Roguedas AM ，Genestet M ，Volant A ，Le Nen D ... -  《-》

Mycobacterium marinum infection following contact with reptiles: vivarium granuloma.

A 19-year-old man presented with a 1.5-cm nodule on the first dorsal metacarpal ray. The patient denied having contact with fish tanks or fish, but recalled handling many reptiles without gloves in the vivarium where he worked. A culture of a skin biopsy specimen yielded Mycobacterium marinum. The clinical outcome was favourable after a 2-week course of intramuscular gentamicin (180 mg daily) combined with a 6-week course of oral clarithromycin (500 mg twice a day). Doctors should be aware that vivariums, in addition to fish tanks, can be sources of M. marinum exposure.

Bouricha M ，Castan B ，Duchene-Parisi E ，Drancourt M ... -  《-》

[Cutaneous infection with Mycobacterium marinum. successful therapy with rifampicin and clarithromycin].

Brans R ，Rübben A ，Poblete-Gutiérrez P 《-》