Is there an Association between Dietary Micronutrients Intake and Bone Fractures among Malaysian Reproductive-Age Women? The PURE Malaysia Study.

Background: Bone fractures represent a significant health issue and impose a considerable burden on healthcare systems globally. However, data pertaining to bone fractures, especially among reproductive-age women in Malaysia, are very limited. Micronutrients like calcium, magnesium and phosphorus play vital roles in bone health, influencing bone mineral density and fracture risk. The objective of this study was to determine the prevalence of bone fractures among reproductive-age women and the association with dietary micronutrient intakes. Methods: In this cross-sectional study, a total of 1,730 participants of reproductive-age women from the Malaysia Prospective Urban and Rural Epidemiological (PURE) study were recruited. The participants' dietary intakes were assessed using a validated semi-quantitative food frequency questionnaire (FFQ). Selected micronutrients in the participants' diets were calculated using the Malaysian food composition and the US Department of Agriculture food composition databases. The association between micronutrient intakes, comorbidities and physical activity levels with bone fractures were evaluated to identify predictors of bone fractures among reproductive-age women. Results: The prevalence of bone fractures among Malaysian reproductive-age women was low (3.7%). The multiple logistic regression analysis showed that none of the micronutrients was associated with bone fractures. However, factors of diabetes and passive smoking in this study showed 2.6- and 4.0-times-higher odds of having bone fractures, respectively (AOR 2.580; 95% CI: 1.173-5.672) and (AOR 4.012; 95% CI: 2.265-7.107). Conclusions: It was found that the majority of women in this study were taking lower micronutrient intakes of calcium, magnesium, and vitamin K than the Malaysia recommended nutrient intakes (RNI). Although this study showed that a low micronutrient intake is not significantly associated with bone fractures, it is recommended that future studies focus on controlled trials or prospective data analyses to establish causal relationships and the optimal micronutrient requirements for maintaining strong and healthy bones in women of reproductive age.

Md Isa Z ，Mohd Ahwan NA ，Ismail NH ，Ismail R ，Tamil AM ，Jaafar MH ，Mat-Nasir N ，Nik Mohd Nasir NM ，Ab Razak NH ，Yusof KH ... -  《Annals of Global Health》

Dietary micronutrient intakes among women of reproductive age in Mumbai slums.

Nunn RL ，Kehoe SH ，Chopra H ，Sahariah SA ，Gandhi M ，Di Gravio C ，Coakley PJ ，Cox VA ，Sane H ，Shivshankaran D ，Marley-Zagar E ，Margetts BM ，Jackson AA ，Potdar RD ，Fall CHD ... -  《-》

Exploring the FAO Minimum Dietary Diversity Indicator as a Suitable Proxy of Micronutrient Adequacy in Men and Women Across Reproductive and Non-reproductive Ages in 8 Latin American Countries.

Gómez G ，Monge-Rojas R ，Vargas-Quesada R ，Previdelli AN ，Quesada D ，Kovalskys I ，Herrera-Cuenca M ，Cortes LY ，García MCY ，Liria-Domínguez R ，Rigotti A ，Fisberg RM ，Ferrari G ，Fisberg M ，Brenes JC ... -  《-》

A Landscape of Micronutrient Dietary Intake by 15- to 65-Years-Old Urban Population in 8 Latin American Countries: Results From the Latin American Study of Health and Nutrition.

Monge-Rojas R ，Vargas-Quesada R ，Previdelli AN ，Kovalskys I ，Herrera-Cuenca M ，Cortés LY ，García MCY ，Liria-Domínguez R ，Rigotti A ，Fisberg RM ，Ferrari G ，Fisberg M ，Gómez G ... -  《-》

Vitamin D and Calcium Intakes, Physical Activity, and Calcaneus BMC among School-Going 13-Year Old Malaysian Adolescents.

Suriawati AA ，Majid HA ，Al-Sadat N ，Mohamed MN ，Jalaludin MY ... -  《Nutrients》