Assessing the HIV care continuum among transgender women during 11 years of follow-up: results from the Netherlands' ATHENA observational cohort.

Transgender women are at increased risk of acquiring HIV. Earlier studies reported lower retention in HIV care, antiretroviral therapy uptake, adherence and viral suppression. We assessed the stages of the HIV care continuum of transgender women in the Netherlands over an 11-year period. In addition, we assessed new HIV diagnoses and late presentation, as well as disengagement from care, between 2011 and 2021. Using data from the Dutch national ATHENA cohort, we separately assessed viral suppression, as well as time to achieving viral suppression, among transgender women for each year between 2011 and 2021. We also assessed trends in new HIV diagnoses and late presentation (CD4 count of <350 cells/µl and/or AIDS at diagnosis), and disengagement from care. Between 2011 and 2021, a total of 260 transgender women attended at least one HIV clinical visit. Across all years, <90% of transgender women were virally suppressed (207/239 [87%] in 2021). The number of new HIV diagnoses fluctuated for transgender women (ptrend = 0.053) and late presentation was common (ranging between 10% and 67% of new HIV diagnoses). Of the 260 transgender women, 26 (10%) disengaged from care between 2011 and 2021 (incidence rate = 1.10 per 100 person-years, 95% confidence interval = 0.75-1.61). Between 2011 and 2021, less than 90% of transgender women linked to HIV care were virally suppressed. Late presentation at the time of diagnosis and disengagement from care were common. Efforts are needed to identify barriers to early HIV diagnosis and to optimize the different steps across the care continuum for transgender women.

Jongen VW ，Daans C ，van Sighem A ，Schim van der Loeff M ，Hage K ，Welling C ，von Vaupel-Klein A ，den Heijer M ，Peters EJG ，van der Valk M ，Reiss P ，Prins M ，Hoornenborg E ，ATHENA observational HIV cohort ... -  《Journal of the International AIDS Society》

HIV testing and the HIV care continuum among sub-Saharan African men who have sex with men and transgender women screened for participation in HPTN 075.

Sandfort TGM ，Dominguez K ，Kayange N ，Ogendo A ，Panchia R ，Chen YQ ，Chege W ，Cummings V ，Guo X ，Hamilton EL ，Stirratt M ，Eshleman SH ... -  《PLoS One》

The HIV Care Continuum: Changes over Time in Retention in Care and Viral Suppression.

Yehia BR ，Stephens-Shields AJ ，Fleishman JA ，Berry SA ，Agwu AL ，Metlay JP ，Moore RD ，Christopher Mathews W ，Nijhawan A ，Rutstein R ，Gaur AH ，Gebo KA ，HIV Research Network ... -  《PLoS One》

HIV Diagnoses and Care Among Transgender Persons and Comparison With Men Who Have Sex With Men: New York City, 2006-2011.

Wiewel EW ，Torian LV ，Merchant P ，Braunstein SL ，Shepard CW ... -  《-》

Service utilization and HIV outcomes among transgender women receiving Ryan White Part A services in New York City.

Thomas JA ，Irvine MK ，Xia Q ，Harriman GA ... -  《PLoS One》