US trends of in-hospital morbidity and mortality for acute myocardial infarctions complicated by cardiogenic shock.

There is limited real-world data highlighting recent temporal in-hospital morbidity and mortality trends for cases of acute myocardial infarction complicated by cardiogenic shock. The role of mechanical circulatory support within this patient population remains unclear. The US National Inpatient Sample database was sampled from 2011 to 2018 identifying 206,396 hospitalizations with a primary admission diagnosis of ST- or Non-ST elevation myocardial infarction complicated by cardiogenic shock. The primary outcomes included trends of all-cause in-hospital mortality, mechanical circulatory support use, and sex-specific trends for acute myocardial infarction complicated by cardiogenic shock (AMI-CS) over the study period. The annual number of AMI-CS hospitalizations increased from 22,851 in 2011 to 30,015 in 2018 and in-hospital mortality trends remained similar (42.9 % to 43.7 %, ptrend < 0.001). The proportion of patients receiving any temporary MCS device decreased (46.4 % to 44.4 %). The use of intra-aortic balloon pump (IABP) decreased (44.9 % to 32.9 %) and the use of any other non-IABP MCS device increased (2.5 % to 15.6 %), ptrend<0.001. Sex-specific mortality indicate female in-hospital mortality remained similar (50.3 % to 51 %, ptrend<0.001), but higher than male in-hospital mortality, which increased non-significantly (38.8 % to 40.2 %, ptrend = 0.372). From 2011 to 2018, hospitalizations for AMI-CS patients have increased in number. However, there has been no recent appreciable change in AMI-CS mortality despite a changing treatment landscape with decreasing use of IABPs and increasing use of non-IABP MCS devices. Further research is necessary to examine the appropriate use of MCS devices within this population.

Koester M ，Dangl M ，Albosta M ，Grant J ，Maning J ，Colombo R ... -  《-》

Trends in mechanical circulatory support use and hospital mortality among patients with acute myocardial infarction and non-infarction related cardiogenic shock in the United States.

Shah M ，Patnaik S ，Patel B ，Ram P ，Garg L ，Agarwal M ，Agrawal S ，Arora S ，Patel N ，Wald J ，Jorde UP ... -  《-》

Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock.

Dhruva SS ，Ross JS ，Mortazavi BJ ，Hurley NC ，Krumholz HM ，Curtis JP ，Berkowitz A ，Masoudi FA ，Messenger JC ，Parzynski CS ，Ngufor C ，Girotra S ，Amin AP ，Shah ND ，Desai NR ... -  《-》

Hospital Variation in the Utilization of Short-Term Nondurable Mechanical Circulatory Support in Myocardial Infarction Complicated by Cardiogenic Shock.

Strom JB ，Zhao Y ，Shen C ，Chung M ，Pinto DS ，Popma JJ ，Cohen DJ ，Yeh RW ... -  《-》

Use of Mechanical Circulatory Support Devices Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock.

Dhruva SS ，Ross JS ，Mortazavi BJ ，Hurley NC ，Krumholz HM ，Curtis JP ，Berkowitz AP ，Masoudi FA ，Messenger JC ，Parzynski CS ，Ngufor CG ，Girotra S ，Amin AP ，Shah ND ，Desai NR ... -  《JAMA Network Open》