Electromyographic Evaluation of Vocal Folds in Patients With Laryngeal Paralysis Referred for Injection Laryngoplasty.

According to the literature, almost 80% of the patients diagnosed with permanent unilateral laryngeal paralysis experience vocal disability. Laryngeal electromyography (LEMG) provides information on the characteristics and progression of the disease process, allowing for optimal treatment. The aim of this study was to evaluate LEMG recordings in patients with unilateral vocal fold (VF) immobility referred for injection laryngoplasty (IL). 17 patients with unilateral laryngeal immobilisation as an iatrogenic complication after neck surgery. The patients were referred for IL surgery due to glottic insufficiency. All patients underwent a preoperative otolaryngologic-phoniatric evaluation with perceptual and acoustic voice assessment and LEMG. Patients with unilateral VF immobilisation referred for injection laryngoplasty for glottal insufficiency show significant differences on LEMG between the mobile and immobile folds. In these patients, electromyography (EMG) features of the thyroarytenoid (TA) muscle correlate with the severity of breathiness in the voice and pathological variation in the fundamental frequency. Despite the lack of mobility and features of VF atrophy, only 12% meet the electromyographic criterion for vocal fold paralysis. The immobile VF has a poorer recording from the TA muscle, the more material needs to be injected to surgically model the glottis during IL. This study demonstrated that LEMG is a valuable criterion for qualifying patients for injection laryngoplasty in unilateral vocal fold paralysis.

Krasnodębska P ，Miaśkiewicz B ，Szkiełkowska A 《-》

Vocal fold electromyography in patients with endoscopic features of unilateral laryngeal paralysis.

Krasnodębska P ，Miaśkiewicz B ，Szkiełkowska A ，Skarżyński H ... -  《-》

Laryngeal electromyography-guided hyaluronic acid vocal fold injection for unilateral vocal fold paralysis: a prospective long-term follow-up outcome report.

Wang CC ，Chang MH ，Jiang RS ，Lai HC ，De Virgilio A ，Wang CP ，Wu SH ，Liu SA ，Liang KL ... -  《-》

Effect of intralaryngeal muscle synkinesis on perception of voice handicap in patients with unilateral vocal fold paralysis.

Intralaryngeal muscle synkinesis associated with unilateral vocal fold paralysis (UVFP) is thought to preserve thyroarytenoid-lateral cricoarytenoid muscle complex tone, resulting in a better voice despite the presence of vocal fold paralysis (VFP). This study compares voice handicap in patients with unilateral VFP (UVFP) with and without evidence of adductory synkinesis on laryngeal electromyography (LEMG). Retrospective review of LEMG data and Voice Handicap Index-10 (VHI-10) scores of patients diagnosed with permanent UVFP. LEMG was performed within 1 to 6 months post onset of UVFP. Patients were stratified into two groups: 1) recurrent laryngeal nerve (RLN) neuropathy with synkinesis and 2) RLN neuropathy without synkinesis. Synkinesis was diagnosed when the sniff to phonation maximum amplitude ratio was ≥0.65. VHI-10 scores at 6-month follow-up were recorded. Four hundred forty-nine patients with UVFP and who had an LEMG were reviewed. Eighty-three patients met the inclusion criteria, with 16 in group 1 and 67 in group 2. There was no significant difference between the groups with regard to age, timing of LEMG from onset of VFP, number of patients undergoing temporary vocal fold injection or use of off-label nimodipine. Average VHI-10 scores at 6 months post onset of VFP were 14.4 ± 10.6 for patients with LEMG-identified synkinesis (group 1) and 21.0 ± 10.1 for patients with no LEMG evidence of synkinesis (group 2). This was statistically significant (P = .02). Patients with unilateral vocal fold paralysis and LEMG evidence of laryngeal synkinesis are more likely to have less perceived voice handicap than those without synkinesis. 4. Laryngoscope, 127:1628-1632, 2017.

Lin RJ ，Munin MC ，Rosen CA ，Smith LJ ... -  《-》

Vocal Fold Paresis: Incidence, and the Relationship between Voice Handicap Index and Laryngeal EMG Findings.

To determine whether there is a correlation between Voice Handicap Index 10 (VHI-10) and degree of vocal fold paresis as determined by laryngeal EMG. Secondary objective was to determine the incidence of vocal fold paresis in a tertiary laryngology practice. A retrospective chart review of all new voice patients seen by the senior author (RTS) from January 1, 2016 to December 31, 2017. Subjects completed VHI at their initial visit. Patients were examined with flexible and rigid laryngoscopy and videostroboscopy and referred for laryngeal electromyography (LEMG) if neuromuscular weakness was suspected. LEMG was used to identify the affected nerves and to quantify subjectively the degree of paresis. Patients who did not complete LEMG and or handicap index were excluded from the correlation analysis. The prevalence of vocal fold paresis was determined by reviewing the records of each subject. The number of patients diagnosed clinically with paresis or paralysis and referred for LEMG was documented. The subjects, who had paresis confirmed on LEMG (n = 210) were grouped according to the nerves involved and by the degree of paresis. The unilateral superior laryngeal nerve and ipsilateral recurrent laryngeal nerve paresis group (n = 29) had a reasonably even distribution of patients in each sub-group (n = 11; 12; 6) and was analyzed for correlation. There was a strong positive correlation between the degree of paresis and the VHI score (r = 0.59, P < 0.001). Other groups did not have an even distribution among sub-groups and could not be to be analyzed for correlation. The senior author examined 344 new voice patients during years of 2016 and 2017. Based on laryngoscopy, 335 patients were referred for LEMG (97.4%). Two hundred thirty-seven patients had LEMG performed, and 234 patients confirmed to have vocal fold paresis were confirmed (98.7%.). The incidence of vocal fold paresis in subjects who underwent LEMG or who had normal motion during laryngoscopy was 95.1% (234 out of 246). The incidence in the 98 subjects who did not complete the recommended LEMG is unknown. The unilateral superior laryngeal nerve with ipsilateral recurrent laryngeal nerve paresis was the only group that allowed for analysis whether patient's perception of their voice problem as measured VHI-10 correlated with increasing degree of vocal fold paresis. A strong significant positive correlation in this group was identified. Additional studies with a larger patient cohort are recommended.

Daggumati S ，Panossian M D H ，Sataloff M D D M A F A C S RT 《-》