Complete mimicry: Rhabdomyosarcoma with FUS::TFCP2 fusion masquerading as carcinoma-diagnostic challenge and report of two cases.

Rhabdomyosarcomas (RMS) are malignant mesenchymal tumors with skeletal muscle differentiation which are classified into alveolar, embryonal, pleomorphic, and spindle cell/sclerosing RMS. Within the spindle cell/sclerosing RMS tumor type there is a recently recognized sub-type categorized as intraosseous spindle cell RMS with TFCP2/NCOA2 gene fusion. This rare tumor is highly aggressive with predominant involvement of the craniofacial and pelvic bones with approximately 30 cases reported to date. Histopathologic features include spindle cell and epithelioid morphology with a characteristic co-expression of epithelial markers, myogenic markers, and ALK1 expression. We report two cases of gnathic spindle cell/sclerosing RMS with FUS::TFCP2 gene fusion that were initially interpreted as carcinomas by referring institutions and later reclassified when encountered in our practice after additional work-up and molecular characterization.

Carrillo-Ng H ，Liang Y ，Chang S ，Afkhami M ，Gernon T ，Bell D ，Arias-Stella JA ... -  《-》

Epithelioid and spindle cell rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusion: report of two cases.

Chrisinger JSA ，Wehrli B ，Dickson BC ，Fasih S ，Hirbe AC ，Shultz DB ，Zadeh G ，Gupta AA ，Demicco EG ... -  《-》

Rhabdomyosarcoma With FUS::TFCP2 Fusion in the Mandible: A Rare Aggressive Subtype, but Can Be Misdiagnosed as Ossifying Fibroma.

Zhong P ，Wei S ，Xiao H ，Zeng Y ... -  《-》

Rhabdomyosarcoma With FUS::TFCP2 Fusion in the Scalp: A Rare Case Report Depicting Round and Spindle cell Morphology.

Ishiyama T ，Kato I ，Ito J ，Matsumura M ，Saito K ，Kawabata Y ，Kato S ，Takeyama M ，Fujii S ... -  《-》

Spindle cell rhabdomyosarcomas: With TFCP2 rearrangements, and novel EWSR1::ZBTB41 and PLOD2::RBM6 gene fusions. A study of five cases and review of the literature.

Bradová M ，Mosaieby E ，Michal M ，Vaněček T ，Ing SK ，Grossmann P ，Koshyk O ，Kinkor Z ，Laciok Š ，Nemcová A ，Straka Ľ ，Farkas M ，Michal M ，Švajdler M ... -  《-》