Hypocalcemic cardiomyopathy: A case report.

Hypocalcemia and its related symptoms are common manifestations in postsurgical hypoparathyroidism, but patients with hypocalcemia manifested as heart failure is rare and few cases are reported in the literature. Here we reported a 58-year-old female with hypoparathyroidism and uncontrolled hypocalcemia after thyroidectomy, presented with acute heart failure, accompanied with enlargement and reduced ejection fraction of left ventricle. She was refractory to guideline-directed medical therapy for heart failure including digitalis and diuretics. However, her symptoms resolved and cardiac function improved dramatically after normalization of serum calcium level. This rare case highlights the pivotal role of calcium in maintaining cardiac function and the importance of treating underlying reversible causes of heart failure. For patients with hypoparathyroidism, it is essential to get standard treatment to avoid development of heart failure and hypocalcemia related syndromes.

Wen Y ，Luo X 《Frontiers in Cardiovascular Medicine》

Hypocalcemic cardiomyopathy - A rare and reversible entity.

Calcium plays a vital key role in cardiac automatism and excitation-contraction coupling, with low serum levels associated with myocardial contractility compromise especially if myocardial sarcoplasmic reticulum is unable to maintain enough calcium content to initiate normal cardiac contraction. We present a 42-year-old woman with postsurgical untreated hypoparathyroidism and severe hypocalcaemia manifested as acute heart failure, without underlying known cardiac disease. Hypocalcaemia is a rare and potentially reversible cause of cardiomyopathy, with very few cases reported in the literature. Restoration to normal serum calcium levels usually leads to a rapid improvement of cardiac function. This rare case report highlights the importance of considering hypocalcaemia as a potentially reversible cause of severe cardiac dysfunction. Exclusion of hypocalcemia due to surgical hypoparathyroidism is mandatory in any individual with acute heart failure previously subjected to thyroidectomy.

da Silva Santos T ，de Carvalho AC 《-》

[Hypocalcemia-induced heart failure as the initial symptom of hypoparathyroidism].

Koch A ，Hofbeck M ，Dörr HG ，Singer H ... -  《-》

Hypocalcemic cardiomyopathy after parathyroidectomy in a patient with uremia: A case report and literature review.

Zhang W ，Xue F ，Bu Q ，Liu X ... -  《-》

Hypocalcemic cardiomyopathy with heart failure: A rare Case report.

Kharel M ，Subedi A ，Hossain MF 《Clinical Case Reports》