Primary signet ring cell carcinoma of the male urethra.

Malignant tumours of the male urethra are rare and commonly present at an advanced stage. The most common type of urethral cancer is urothelial carcinoma, followed by squamous cell carcinoma. Less than 5% of urethral cancers are adenocarcinoma. We report a young male with signet ring cell carcinoma of the membranous urethra who presented with recurrent lower urinary tract symptoms. Although he was initially treated for a urinary tract infection, the correct diagnosis was made with an appropriate imaging workup. He underwent radical urethrectomy with total pelvic exenteration with bilateral extended pelvic lymph node dissection. Ileal conduit and colostomy were performed as urinary and bowel diversions, respectively. The patient received adjuvant chemotherapy, however, succumbed to COVID-19 8 months after the procedure. This case has been presented to highlight the high index of suspicion required to diagnose this rare malignancy.

Joseph DDC ，Chinnathambi J ，Jamburaj A 《-》

Primary signet ring cell carcinoma of female urethra.

Suzuki K ，Morita T ，Tokue A 《-》

Adenocarcinoma of the urethra: A rare subtype of urethral cancer.

Urethral adenocarcinoma (UA) is a rare type of urethral cancer with a poor prognosis. We present a case of UA of intestinal subtype in a 57-year-old patient who initially had lower urinary tract symptoms and was subsequently found to have a urethral lesion in a urethral diverticulum on pelvic MRI which was confirmed on biopsy. She had neoadjuvant chemotherapy followed by open anterior pelvic exenteration, complete urethrectomy and ileal conduit urinary diversion. She required adjuvant chemotherapy for local invasion and a metastasis in the uterus but developed progressive metastatic disease and succumbed to the disease 13-months after surgery.

Viswambaram P ，Oey O ，Swarbrick N ，Hayne D ... -  《Urology Case Reports》

Primary adenocarcinoma of bulbomembranous urethra: An exceedingly rare carcinoma in a male patient.

Stukalin I ，Gao Y ，Spaner S ，Trpkov K ，Gotto G ... -  《-》

Management of primary adenocarcinoma of the female urethra: Report of two cases and review of the literature.

Wang X ，Bai P ，Su H ，Luo G ，Zhong Z ，Zhao X ... -  《-》