Rare Manifestation of Sjögren's Syndrome as Unilateral Facial Paralysis: A Case Report and Literature Review.

Herein, we present a unique case of Sjögren's syndrome (SS) first presenting as facial palsy, as well as a literature review of case reports describing SS-associated facial paralysis. A PubMed search for papers containing the keywords Sjögren's syndrome or Sjögren's disease, as well as facial paralysis, facial paresis, facial palsy, or Bell's palsy, was performed. Articles not in English and cases of SS not involving facial paralysis were excluded. Appropriate articles were reviewed for patient demographics and symptoms of SS, including laterality of facial paralysis, cranial nerve involvement, and comorbid diseases. House-Brackmann grades were annotated based on either assignment by individual case reports or the authors' descriptions when sufficient details were present. Of 43 peer-reviewed articles found, 14 were both in the English language and provided adequate information on a total of 16 patients with facial paralysis and SS diagnosis. Ultimately, SS and other systemic autoimmune disorders should be considered in the differential diagnosis of patients presenting with insidious onset facial paralysis.

Montgomery EA ，Patel JA ，Boone RE ，Teixeira JC ，Vincent AG ，Hohman MH ... -  《-》

Bilateral facial paralysis as a rare neurological manifestation of primary Sjögren's syndrome: case-based review.

Wei Z ，Jiaying S ，Junhong G 《-》

Sjogren's syndrome associated with bilateral peripheral facial paralysis.

Sjogren's Syndrome (SS) is a chronic autoimmune disorder that may be complicated by neurological dysfunctions. The involvement of cranial nerves in SS was described as a very rare complication. Moreover, bilateral peripheral facial paralysis associated with SS has been described only in 3 patients in the literature and the first case was described by Henrik Sjogren himself in 1935. We report a 59-year-old female with bilateral peripheral facial paralysis associated with Sjogren's syndrome. She was treated with 5-day IVIG consecutively and continued oral methylprednisolone 16mg/day and almost fully recovered at 2 months of follow-up examination. Acute bilateral peripheral facial palsy in SS is a very rare condition and Lyme disease, Guillain-Barré syndrome, HIV infection, and central nervous system lymphoma should be considered in the differential diagnosis. As a result, SS should be considered as an underlying cause of bilateral facial paralysis.

Isik K ，Morkavuk G ，Koc G ，Odabasi Z ... -  《Neurosciences》

Bilateral facial palsy as the first presentation of primary Sjögren's syndrome: a case report and review of literature.

Alinezhad N ，Habibagahi Z ，Ostovan VR 《-》

[Recurrent facial palsy, primary Gougerot-Sjögren's syndrome and vitamin B12 deficiency].

Rousso E ，Noel E ，Brogard JM ，Blicklé JF ，Andrès E ... -  《PRESSE MEDICALE》