Ecotoxicological effects of microplastics on aquatic organisms: a review.

Microplastics   ( <5 mm), which are classified based on primary or secondary sources, are widely distributed in the environment and exert significant effects on aquatic life forms; however, evidence regarding the ecotoxicological effects of microplastics on aquatic organisms is still limited. This research aims at filling a knowledge gap regarding generation sources, distribution, physicochemical properties, and biological behavior of microplastics (MP) in aquatic environments and their interaction with aquatic organisms. The literature indicates that concentrations of MPs observed in such environments are higher than the threshold for safe concentration (6650 buoyant particles/m3). MPs having large specific surface area, low polarity, and hydrophobic properties have been shown to absorb dichlorodiphenyltrichloroethane (DDT), polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbon (PAHs), bisphenol A (BPA), polyfluoroalkyl substances (PFAS), antibiotics, and heavy metals. MPs adsorb large amounts of toxic organic chemicals (18,700 ng/g PCBs; 24,000 ng/g PAHs) and heavy metals (0.21-430 μg/g Cr; 0.0029-930 μg/g Cd; 0.35-2.89 μg/g As; 0.26-698,000 μg/g Pb). MPs originating from polystyrene (PS), polypropylene (PP), and polyvinylchloride (PVC) show greater toxicity toward aquatic organisms, with effects on the immune system, reproductive system, nervous system, and endocrine system. Thus, elucidating the cumulative toxic expression of MPs in different polluted environments is critical.

Vo HC ，Pham MH 《-》

Microplastics altered contaminant behavior and toxicity in natural waters.

Microplastics (MPs) have received an increasing attention because of their ubiquitous presence and aquatic toxicity associated with MPs and MP-bound contaminants in the natural water. This review is to critically examine the chemical additives leached from MPs, the altered contaminant behaviors and the resulting changes in their aquatic ecotoxicity. Available data suggest that heavy metals Zn, Cr, Pb, and Cd regulated and present in plastics at the sub-mg g-1 to mg g-1 level can leach a significant amount depending on MPs size, aging, pH, and salinity conditions. MP-bound organic contaminants are primarily additive-derived (e.g., brominated diphenyl ethers, nonylphenol, and bisphenol A) at the µg g-1 to mg g-1 level, and secondarily pyrogenic and legacy origins (e.g., PAHs and PCBs) in the range of ng g-1 and mg g-1. MPs tend to have higher but more variable sorption capacities for organic compounds than metals (1.77 ± 2.34 vs. 0.82 ± 0.94 mg g-1). MPs alter the behavior of heavy metals through the electrostatic interactions and surface complexation, while the transport of additive derived organic compounds are altered primarily through hydrophobic effect as supported by a positive correlation (R2 = 0.71) between the logarithmic MPs-adsorbed concentrations and octanol/water partition coefficients (KOW) of organic compounds. MPs constitute less than 0.01% of the total mass of aquatic particulates in typical waters, but play a discernible role in the local partitioning and long-distance movement of contaminants. MPs alone exert higher toxicity to invertebrates than algae; however, when MPs co-occur with pollutants, both synergistic and antagonistic toxicities are observed depending mainly on the ingestibility of MPs, the extent of sorption, MPs as a transport vector or a sink to scavenge pollutants. We finally suggest several key areas of future research directions and needed data concerning the role of MPs in mitigating pollutant leaching, transport and risk under conditions mimicking natural and polluted waters.

Ding T ，Wei L ，Hou Z ，Li J ，Zhang C ，Lin D ... -  《-》

Current status of microplastics pollution in the aquatic environment, interaction with other pollutants, and effects on aquatic organisms.

Microplastics, as emerging pollutants, have received great attention in the past few decades due to its adverse effects on the environment. Microplastics are ubiquitous in the atmosphere, soil, and water bodies, and mostly reported in aqueous environment. This paper summarizes the abundance and types of microplastics in different aqueous environments and discusses the interactions of microplastics with other contaminants such as polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), antibiotics, and heavy metals. The toxicity of microplastics to aquatic organisms and microorganisms is addressed. Particularly, the combined toxic effects of microplastics and other pollutants are discussed, demonstrating either synergetic or antagonistic effects. Future prospectives should be focused on the characterization of different types and shapes of microplastics, the standardization of microplastic units, exploring the interaction and toxicity of microplastics with other pollutants, and the degradation of microplastics, for a better understanding of the ecological risks of microplastics.

Zhang T ，Jiang B ，Xing Y ，Ya H ，Lv M ，Wang X ... -  《-》

Toxicity assessment of pollutants sorbed on environmental sample microplastics collected on beaches: Part I-adverse effects on fish cell line.

Microplastics (MPs), are tiny plastic fragments from 1 μm to 5 mm generally found in the aquatic environment which can be easily ingested by organisms and may cause chronic physical but also toxicological effects. Toxicological assays on fish cell lines are commonly used as an alternative tool to provide fast and reliable assessment of the toxic and ecotoxic properties of chemicals or mixtures. Rainbow trout liver cell line (RTLW-1) was used to evaluate the toxicity of pollutants sorbed to MPs sampled in sandy beaches from different islands around the world during the first Race for Water Odyssey in 2015. The collected MPs were analyzed for polymer composition and associated persistent organic pollutants: polycyclic aromatic hydrocarbons (PAHs), polychlorobiphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT). In addition, DMSO-extracts from virgin MPs, MPs artificially coated with B[a]P and environmental MPs were analyzed with different bioassays: MTT reduction assay (MTT), ethoxyresorufin-O-deethylase (EROD) assay and comet assay. Microplastics from sand beaches were dominated by polyethylene, followed by polypropylene fragments with variable proportions. Organic pollutants found on plastic from beach sampling was PAHs (2-71 ng g-1). Samples from Bermuda (Somerset Long Bay) and Hawaii (Makapu'u) showed the highest concentration of PAHs and DDT respectively. No toxicity was observed for virgin microplastics. No cytotoxicity was observed on cells exposed to MP extract. However, EROD activity was induced and differently modulated depending on the MPs locations suggesting presence of different pollutants or additives in extract. DNA damage was observed after exposure to four microplastics samples on the six tested. Modification of EROD activity level and DNA damage rate highlight MPs extract toxicity on fish cell line.

Pannetier P ，Cachot J ，Clérandeau C ，Faure F ，Van Arkel K ，de Alencastro LF ，Levasseur C ，Sciacca F ，Bourgeois JP ，Morin B ... -  《-》

Interactions and effects of microplastics with heavy metals in aquatic and terrestrial environments.

Contamination of waters and soils with microplastics (MPs) is an emerging environmental issue worldwide. MPs constitute a cocktail of various additives and polymers besides adsorbing toxic heavy metals from the environment. This co-occurrence of MPs with heavy metals poses a threat to the health of organisms and is poorly understood. Ingestion of MPs contaminated with heavy metals may also result in subsequent transfer of heavy metals up in the food chain. MPs surfaces play a crucial role in the adsorption of heavy metals. Aged/biofouled MPs facilitate greater adsorption of metals and certain microplastic (MP) polymers adsorb some metals more specifically. External factors involved in the process of adsorption/accumulation of heavy metals are the solution pH, salinity, and the concentration of relevant heavy metals in the media. Desorption greatly depends upon pH of the external solution. This is more concerning as the guts/digestive systems of organisms have low pH which could enhance the desorption of toxic metals and making them accumulate in their bodies. The aim of this article is to discuss the abundance, distribution, adsorption, and desorption behavior of MPs for heavy metals, and their combined toxic effects on flora and fauna based on the limited research on this topic in the literature. There is an overarching need to understand the interactions of MPs with heavy metals in different ecosystems so that the extent of ecotoxic effects they pose could be assessed which would help in the environmental regulation of these pollutants.

Khalid N ，Aqeel M ，Noman A ，Khan SM ，Akhter N ... -  《-》