Magnetic resonance cisternography imaging findings related to the leakage of Gadolinium into the subarachnoid space.

To identify magnetic resonance cisternography (MRC) imaging findings related to Gadolinium-based contrast agent (GBCA) leakage into the subarachnoid space. The number of voxels of GBCA leakage (V-leak) on 3D-real inversion recovery images was measured in 56 patients scanned 4 h post-intravenous GBCA injection. Bridging veins (BVs) were identified on MRC. The numbers of BVs with surrounding cystic structures (BV-cyst), with arachnoid granulations protruding into the superior sagittal sinus (BV-AG-SSS) and the skull (BV-AG-skull), and including any of these factors (BV-incl) were recorded. Correlations between these variables and V-leak were examined based on the Spearman's rank correlation coefficient. Receiver-operating characteristic (ROC) curves were generated to investigate the predictive performance of GBCA leakage. V-leak and the number of BV-incl were strongly correlated (r = 0.609, p < 0.0001). The numbers of BV-cyst and BV-AG-skull had weaker correlations with V-leak (r = 0.364, p = 0.006; r = 0.311, p = 0.020, respectively). The number of BV-AG-SSS was not correlated with V-leak. The ROC curve for contrast leakage exceeding 1000 voxels and the number of BV-incl had moderate accuracy, with an area under the curve of 0.871. The number of BV-incl may be a predictor of GBCA leakage and a biomarker for waste drainage function without using GBCA.

Nakamichi R ，Taoka T ，Kawai H ，Yoshida T ，Sone M ，Naganawa S ... -  《-》

Relationship between Parasagittal Perivenous Cysts and Leakage of Gadolinium-based Contrast Agents into the Subarachnoid Space around the Cortical Veins after Intravenous Administration.

Naganawa S ，Ito R ，Nakamichi R ，Kawamura M ，Kawai H ，Taoka T ，Yoshida T ，Sone M ... -  《-》

Relationship between Time-dependent Signal Changes in Parasagittal Perivenous Cysts and Leakage of Gadolinium-based Contrast Agents into the Subarachnoid Space.

Naganawa S ，Ito R ，Nakamichi R ，Kawamura M ，Taoka T ，Yoshida T ，Sone M ... -  《-》

Confirmation of Age-dependence in the Leakage of Contrast Medium around the Cortical Veins into Cerebrospinal Fluid after Intravenous Administration of Gadolinium-based Contrast Agent.

Naganawa S ，Ito R ，Kawai H ，Taoka T ，Yoshida T ，Sone M ... -  《-》

Age Dependence of Gadolinium Leakage from the Cortical Veins into the Cerebrospinal Fluid Assessed with Whole Brain 3D-real Inversion Recovery MR Imaging.

Naganawa S ，Nakane T ，Kawai H ，Taoka T ... -  《-》