Implementation Experience With Meningococcal Serogroup B Vaccines in the United States: Impact of a Nonroutine Recommendation.

Meningococcal serogroup B (MenB) is the leading cause of invasive meningococcal disease among US adolescents and young adults, accounting for 62% of cases in 16-23-year-olds in 2018. Since 2015, the Advisory Committee on Immunization Practices (ACIP) has recommended vaccination of healthy adolescents against MenB based on shared clinical decision-making (previously called "Category B" or individual clinical decision-making). However, MenB vaccine coverage and series completion rates remain low. Herein we examine implementation experience of adolescent MenB vaccination in the United States under this nonroutine ACIP recommendation. PubMed was searched for English-language articles published after 2015 examining MenB vaccination implementation in the United States. Studies reporting MenB vaccination awareness, coverage, knowledge of recommendations and implementation barriers or access disparities were included. Identified studies provided evidence that ACIP's MenB vaccination recommendation is poorly understood and prone to misinterpretation by US healthcare providers. Parental awareness of MenB vaccines is low, and racial and socioeconomic disparities exist regarding vaccine receipt. Parents rely on providers to learn about MenB disease risk and benefits of vaccination, with provider recommendations carrying substantial weight in vaccination decisions. Five years of evidence regarding the MenB vaccination implementation experience suggest that the nonstandard recommendation for MenB vaccines is partly responsible for low vaccine coverage. Further, inconsistent implementation of ACIP recommendations could be limiting access to MenB vaccines. Providers need additional support and guidance to implement the shared clinical decision-making recommendation, in turn ensuring equitable access for vaccine-eligible adolescents to enable comprehensive protection against meningococcal disease.

Fergie J ，Howard A ，Huang L ，Srivastava A ... -  《-》

Parental awareness and utilization of meningococcal serogroup B vaccines in the United States.

Srivastava A ，Dempsey A ，Galitsky A ，Fahimi M ，Huang L ... -  《BMC PUBLIC HEALTH》

Exploring meningococcal serogroup B vaccination conversations under shared clinical decision-making in the US.

Herrera-Restrepo O ，Clements DE ，Hebert ZN ，McCracken C ... -  《-》

Disparities in healthcare providers' interpretations and implementations of ACIP's meningococcal vaccine recommendations.

Huang L ，Goren A ，Lee LK ，Li VW ，Dempsey A ，Srivastava A ... -  《-》

Awareness, attitudes, and practices on meningococcal serogroup B vaccination in the United States among parents of older adolescents and among young adults.

Herrera-Restrepo O ，Zhou Z ，Krishnan A ，Conley WJ ，Oladele E ，Multani JK ，Tuly R ，Shi L ，Chen CC ，Preiss S ，Clements DE ... -  《-》