Prognostic nomogram based on the metastatic lymph node ratio for gastric neuroendocrine tumour: SEER database analysis.

The prediction of survival of gastric neuroendocrine tumours (g-NETs) is controversial. Prognostic effects of the metastatic lymph node ratio (LNR) in patients with g-NET were explored, and a nomogram was plotted to predict the survival rates of patients. A longitudinal study conducted on the basis of the Surveillance, Epidemiology, and End Results database. The association between LNR and survival were investigated by using Pearson correlation and Cox regression. Overall survival (OS) and cancer-specific survival (CSS) rates were predicted with the help of nomograms. A total of 315 patients with g-NET diagnosed from 2004 to 2015 were included in this study. LNR was discovered to have a negative correlation with OS and CSS (Pearson correlation coefficients: 0.343 (p<0.001) and 0.389 (p<0.001), respectively). The multivariate analyses indicated age, tumour site, differentiation, T staging, M staging, chemotherapy and LNR to be independent prognostic factors for both OS and CSS. Surgery was also a prognostic determinant for CSS (p=0.003). Concordance indices of the nomograms for OS and CSS were higher than those of the TNM classification (0.772 vs 0.730 and 0.807 vs 0.768, respectively). As per the area under the receiver operating characteristic curve, predictive ability of the nomograms for survival of 1, 3 and 5 years was all better than that of TNM classification. LNR is an independent predictor of g-NETs. The nomograms plotted in this study have a satisfying predictive ability of survival risks and are capable of guiding tailored treatment strategies for patients with g-NET.

Li J ，Lin Y ，Wang Y ，Lin H ，Lin F ，Zhuang Q ，Lin X ，Wu J ... -  《ESMO Open》

A nomogram incorporating treatment data for predicting overall survival in gastroenteropancreatic neuroendocrine tumors: a population-based cohort study.

Wu Z ，Shang G ，Zhang K ，Wang W ，Fan M ，Lin R ... -  《-》

Development and Validation of Prognostic Nomograms Based on Lymph Node Ratio for Young Patients with Gastric Cancer: A SEER-Based Study.

Chen YR ，Tian ZY ，Wang MQ ，Sun ML ，Wu JZ ，Wang XY ... -  《-》

Epidemiologic Trends of and Factors Associated With Overall Survival for Patients With Gastroenteropancreatic Neuroendocrine Tumors in the United States.

Xu Z ，Wang L ，Dai S ，Chen M ，Li F ，Sun J ，Luo F ... -  《JAMA Network Open》

Nomogram individually predicts the overall survival of patients with gastroenteropancreatic neuroendocrine neoplasms.

Fang C ，Wang W ，Feng X ，Sun J ，Zhang Y ，Zeng Y ，Wang J ，Chen H ，Cai M ，Lin J ，Chen M ，Chen Y ，Li Y ，Li S ，Chen J ，Zhou Z ... -  《-》