Microbiology of Hafnia alvei.

Hafnia alvei is a Gram-negative facultatively anaerobic bacillus that constitutes part of the human gut flora. Until recently, H. alvei strains could be mistakenly identified by conventional methods, miniaturisation or automatic systems as members of the Serratia, Escherichia, Citrobacter, Yokenella, Obesumbacterium or Salmonella genera. Consequently, molecular techniques were required for their definitive identification in the clinical laboratory. In addition, a new Hafnia species, H. paralvei, has recently appeared, which undoubtedly includes many of the strains reported in the literature as H. alvei. Alrhough H. alvei isolation from human clinical specimens remains uncommon, the development of drug resistance due to this species is emerging and it is likely that this organism will gain increasing importance in the future. Moreover, although H. alvei shares some virulence mechanisms with other Gram-negative enteropathogens, little is known about the factors that contribute to its pathogenesis in humans. The present article reviews the current identification methods, antimicrobial resistance and virulence factors of this bacterium.

Ramos-Vivas J 《-》

Identification of Hafnia alvei with the MicroScan WalkAway system.

Rodríguez LA ，Vivas J ，Gallardo CS ，Acosta F ，Barbeyto L ，Real F ... -  《-》

Comparative genomic analysis of the Hafnia genus reveals an explicit evolutionary relationship between the species alvei and paralvei and provides insights into pathogenicity.

Yin Z ，Yuan C ，Du Y ，Yang P ，Qian C ，Wei Y ，Zhang S ，Huang D ，Liu B ... -  《BMC GENOMICS》

Natural antimicrobial susceptibility patterns and biochemical identification of Escherichia albertii and Hafnia alvei strains.

Stock I ，Rahman M ，Sherwood KJ ，Wiedemann B ... -  《DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE》

Hafnia paralvei sp. nov., formerly known as Hafnia alvei hybridization group 2.

Huys G ，Cnockaert M ，Abbott SL ，Janda JM ，Vandamme P ... -  《international journal of systematic and evolutionary microbiology》