Miscalculated Lung Shunt Fraction for Planning of Hepatic Radioembolization.

90Y radioembolization is a safe and efficacious treatment option for many patients with unresectable hepatocellular carcinoma. Potential candidates for radioembolization, based on clinical criteria, undergo 99mTc-labeled macroaggregated albumin imaging to determine the extent of hepatopulmonary shunting. Dose selection is based on results from shunt imaging and can exclude patients from radioembolization therapy. We present a case of miscalculated lung shunt fraction and the circumstances that led to the critical error.

Caskey JS ，Kay MD ，McMillan NA ，Kuo PH ，Woodhead GJ ... -  《-》

Indicators of Lung Shunt Fraction Determined by Technetium-99 m Macroaggregated Albumin in Patients with Hepatocellular Carcinoma.

Kallini JR ，Gabr A ，Hickey R ，Kulik L ，Desai K ，Yang Y ，Gates VL ，Riaz A ，Salem R ，Lewandowski RJ ... -  《-》

Diagnosis of Pulmonary Embolism on 99mTc-Labeled Macroaggregated Albumin Lung Imaging After Hepatic Arterial Injection for Planning of Radioembolization.

A 54-year-old man with hepatocellular carcinoma from alcohol-induced cirrhosis presented with hepatic encephalopathy and refractory ascites related to decompensated liver disease. MRI confirmed disease progression adjacent the site of prior radiofrequency ablation, performed 2 years prior, with associated right hepatic vein tumor thrombus. 99mTc-labeled macroaggregated albumin lung shunt imaging performed before 90Y radioembolization identified a left lower lobe wedge-shaped defect, confirmed as pulmonary embolism on CT pulmonary angiography and MRI.

Frazzitta AE ，Kay MD ，Warhadpande D ，Kuo PH ... -  《-》

Chemoembolic hepatopulmonary shunt reduction to allow safe yttrium-90 radioembolization lobectomy of hepatocellular carcinoma.

Gaba RC ，Vanmiddlesworth KA 《-》

Tc-99m-MAA lung shunt fraction before Y-90 radioembolization is low among patients with non-hepatocellular carcinoma malignancies.

Elsayed M ，Martin JG ，Dabrowiecki A ，Goldman DT ，Faraj R ，McMahon JT ，Kokabi N ，Duszak R Jr ，Newsome J ，Bercu ZL ... -  《-》