Neutrophilic dermatosis of the dorsal hands: A review of 123 cases.

Neutrophilic dermatosis of the dorsal hands (NDDH) is an uncommon localized variant of Sweet syndrome first described in 1995. It is characterized by tender erythematous plaques, pustules, and bullae on the dorsa of the hands. A total of 123 cases of NDDH are included in this review. The mean patient age was 62.1 years, and there was a slight female preponderance. Overall, 78.0% of cases had bilateral involvement, and other sites were affected in almost a third of cases. Underlying disease was found in ∼40% of patients, with the most common associations being hematologic disorders (gammopathies, myelodysplasias, or malignancies), recent infection, solid organ tumors, and inflammatory bowel disease. Systemic or topical corticosteroids or both were employed in the treatment of 88.1% of cases, while dapsone, colchicine, and tetracyclines were the most common steroid-sparing agents used. Improvement was often rapid and complete resolution the norm. Although uncommon, NDDH is frequently misdiagnosed, and thus, its exact prevalence is probably underestimated. Misdiagnosis might have significant implications, including treatment delays or incorrect management. Moreover, recognition of NDDH is important, since a correct diagnosis should trigger a search for underlying diseases and proper treatment with corticosteroids, steroid-sparing agents, or both, which is almost invariably curative.

Micallef D ，Bonnici M ，Pisani D ，Boffa MJ ... -  《-》

Neutrophilic Dermatosis of the Hands: A Case Report.

Yaghoobi R ，Bagherani N ，R Smoller B ，Pazyar N ... -  《-》

Neutrophilic Dermatosis of Dorsal Hands and Legs.

Behrangi E ，Rasi A ，Attar B ，Azizian Z ... -  《-》

A case of filgrastim-induced neutrophilic dermatosis of the dorsal hands in a patient with Felty Syndrome.

Joshi TP ，Dokic Y ，Verstovsek G ，Rosen T ... -  《-》

Neutrophilic dermatosis of the dorsal hands associated with hypopharyngeal carcinoma.

Cravo M ，Cardoso JC ，Tellechea O ，Cordeiro MR ，Reis JP ，Figueiredo A ... -  《-》