Quality of Life Before and After Transplantation in Solid Organ Recipients Referred to the North Italy Transplant program (NITp): A Cross-sectional Study.

The interest in health-related quality of life (HR-QoL) has increased in the past few years. The aim of this study was to evaluate the HR-QoL before and after transplantation in solid organ recipients referred to the North Italy Transplant program. This cross-sectional study was performed between 2010 and 2011. All consecutive recipients on the waiting list for liver, heart, or kidney transplantation were included and compared to all consecutive transplanted patients at 6 and 24 months of follow-up after transplantation. The HR-QoL was evaluated with the 36-item Short Form Health Survey (SF-36) and the Profile of Mood States (POMS). Questionnaires were self-reported anonymously. Descriptive statistical analyses were performed. Four hundred eleven patients were interviewed: 146 patients (35.5%) were on the waiting list, 137 (33.3%) were transplanted 6 months before the interview, and 128 (31.1%) were transplanted 24 months before the interview. Patients on the waiting list had a lower SF-36 score for all items than did transplanted patients after both 6 and 24 months. According to POMS results, patients on the waiting list had a higher prevalence of depression, tension, anger, fatigue, and confusion than did transplanted patients. Patients on the waiting list showed a worse quality of life compared to patients after transplantation as demonstrated by SF-36 and POMS results. These findings should be confirmed in a cohort study.

Cannavò A ，Passamonti SM ，Vincenti D ，Aurelio MT ，Torelli R ，Poli F ，Piccolo G ，Cardillo M ，North Italy Transplant program ... -  《-》

Level of Life Quality in Heart and Kidney Transplant Recipients: A Multicenter Study.

The main objective of the researchers was to determine the level of life quality among heart and kidney transplant recipients depending on the time and type of the transplant. The study was conducted using standardized questionnaires: the 36-Item Short-Form Health Survey, Life Orientation Test-Revised, and Hospital Anxiety and Depression Scale. The study included 146 recipients (109 heart transplant recipients and 37 kidney transplant recipients) from 1 to 26 years after the transplantation surgery (mean 9 years). The mean age of the study group was 52 years. The mean time since organ transplantation was 10 years for heart transplantation and 4.3 years for kidney transplantation. The study group obtained a slightly lower score for quality of life compared to the general population. In the Physical Component Summary (PCS), the study participants obtained the highest mean for the domain bodily pain (47.6), while the lowest score was in the domain role physical (41.82). As for the Mental Component Summary (MCS), the highest mean was obtained for the domain vitality (50.57), whereas the lowest one was for the domain role emotional (43.38). In 33% of the participants, risk of depression was identified. Statistically significant differences were observed depending on the type of the transplanted organ in the PCS for the domains general health, physical functioning, and bodily pain and the MCS for role emotional and social functioning. The statistically significant predictors for the PCS domain were the type of transplanted organ, recipients' age, and occurrence of anxiety. In turn, the predictor for the MCS was the occurrence of depression. The quality of life (QOL) assessment varies between kidney and heart transplant recipients. The QOL is determined by the recipients' age and the occurrence of anxiety and depression. The obtained QOL assessment results are slightly lower than those in the general population.

Milaniak I ，Rużyczka EW ，Dębska G ，Król B ，Wierzbicki K ，Tomaszek L ，Przybyłowski P ... -  《-》

Health-related quality of life of transplant recipients: a comparison between lung, kidney, heart, and liver recipients.

Tarabeih M ，Bokek-Cohen Y ，Azuri P 《-》

Longitudinal study of liver transplant recipients' quality of life as a function of their perception of general health: at waiting list and at 3, 6, and 12 months post-transplantation.

The objective of this study was to compare the evolution (at waiting list, and at 3, 6, and 12 months post-transplantation) of quality of life of cadaveric liver transplant recipients as a function of their perception of general health. Two groups (15 patients with better and 15 with worse self-perception of health 1 year after transplantation) were assessed at the pretransplantation and post-transplantation phases using the EuroQol (EQ-5D) questionnaire. Mixed analysis of covariance was performed with 2 factors: phase (at waiting list and at 3, 6, and 12 months post-transplantation) and perception of general health (better and worse). Cohen's d was also calculated. Interactive effects were found in the variables pain/discomfort (P = .010) and anxiety/depression (P = .001). The following simple effects reached large effect sizes. Transplant recipients presented more pain/discomfort when on the waiting list than at 3 months (worse self-perception, P = .022, d = 1.35; better self-perception, P = .001, d = 0.95). At 6 months (P = .001, d = -1.45) and at 12 months (P = .001, d = -1.75), transplant recipients with worse self-perception displayed more pain/discomfort. Transplant recipients with better self-perceived health showed more anxiety/depression when on the waiting list than at 3 months (P = .004, d = 1.49), at 6 months (P = .005, d = 1.48), and at 12 months (P = .001, d = 1.97). Patients with worse self-perception presented more anxiety/depression when on the waiting list than at 6 months (P = .030, d = 1.21) and 12 months compared with at 3 months (P = .011, d = -0.97) and 6 months (P = .001, d = -1.39). At 12 months, transplant recipients with worse self-perception showed more anxiety/depression (P = .001, d = -2.18). Pain/discomfort and, especially, anxiety/depression contribute to liver transplant recipients' worse general health status 1 year after transplantation.

Martín-Rodríguez A ，Fernández-Jiménez E ，Pérez-San-Gregorio MA ，Pérez-Bernal J ，Gómez-Bravo MA ... -  《-》

Exploring quality of life among renal and liver transplant recipients.

Alkatheri A ，Al Bekairy A ，Aburuz S ，Qandil A ，Khalidi N ，Abdullah K ，Al Sayyari S ，Bustami R ，Al Harbi S ，Al Raddadi S ，Al Thiab K ，Bin Saleh K ，Al Shaya A ... -  《-》