Variability of vertical cup to disc ratio measurement and the effects of glaucoma 5-year risk estimation in untreated ocular hypertensive eyes.

To compare the vertical cup to disc ratio (VCDR) measurements obtained with optical coherence tomography (OCT), Heidelberg retina tomography (HRT) and stereophotography of the optic nerve head (ONH) in patients with ocular hypertension (OHT), and their corresponding estimated 5-year risk for development of glaucoma. ONH images of patients with OHT were taken by fundus camera (stereoscopic images), OCT and HRT. Optic disc stereophotographs were evaluated with a stereo-viewer by two glaucoma specialists (SP1 and SP2) and the VCDR was measured with the ImageJ software. VCDR measurements obtained with stereophotography, OCT and HRT were used to calculate the estimated 5-year risk. One hundred and forty eyes of 75 patients with OHT were included. The VCDR values measured by OCT, HRT, SP1 and SP2 were 0.60±0.14, 0.53±0.23, 0.44±0.13 and 0.49±0.10, respectively. The corresponding 5-year risk for development of glaucoma was 19.54%±16.60%, 18.13%±16.96%, 15.64%±14.35% and 16.70%±14.49%, respectively. Different degrees of proportional biases were observed in VCDR measurements obtained with stereophotography, OCT and HRT. The maximum difference of VCDR measurement was 0.64, while the maximum difference of the corresponding 5-year risk was 24.02%. The disagreement in VCDR measured by OCT, HRT and stereophotography in untreated OHT eyes extends to their 5-year risk estimation of glaucoma development.

Chan PP ，Chiu V ，Wong MO 《-》

Agreement between stereoscopic photographs, clinical assessment, Heidelberg retina tomograph and digital stereoscopic optic disc camera in estimating vertical cup:disc ratio.

Jayasundera T ，Danesh-Meyer HV ，Donaldson M ，Gamble G ... -  《CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY》

Correlations Between the Individual Risk for Glaucoma and RNFL and Optic Disc Morphometrical Evaluations in Ocular Hypertensive Patients.

Colombo L ，Bertuzzi F ，Rulli E ，Miglior S ... -  《-》

Comparison of measurement error of Cirrus HD-OCT and Heidelberg Retina Tomograph 3 in patients with early glaucomatous visual field defect.

Shpak AA ，Sevostyanova MK ，Ogorodnikova SN ，Shormaz IN ... -  《-》

Diffuse glaucomatous structural and functional damage in the hemifield without significant pattern loss.

Grewal DS ，Sehi M ，Greenfield DS 《-》