A comprehensive review of web-based non-coding RNA resources for cancer research.

Non-coding RNAs include many kinds of RNAs that did not encode proteins. Recent evidences reveal that ncRNAs play critical roles in initiation and progression of cancers. But it is not easy for cancer biologists and medical doctors to easily know the potential roles of ncRNAs in cancer and retrieve the information of ncRNAs under their investigations. To make the available web-based resources more accessible and understandable, we made a comprehensive review for 49 web-based resources of three types of ncRNAs, i.e., microRNAs (miRNAs), long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs). We also listed some preferred resources for 6 different types of analyses related to ncRNAs.

Zheng Y ，Liu L ，Shukla GC 《-》

A comprehensive review of web-based resources of non-coding RNAs for plant science research.

Liao P ，Li S ，Cui X ，Zheng Y ... -  《International Journal of Biological Sciences》

Non-coding RNA in cancer.

Majority of the human genome is transcribed to RNAs that do not encode proteins. These non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of various cancers. Given the importance of the ncRNAs, the roles of ncRNAs in cancers have been reviewed elsewhere. Thus, in this review, we mainly focus on the recent studies of the function, regulatory mechanism and therapeutic potential of the ncRNAs including microRNA (miRNA), long ncRNA (lncRNA), circular RNA (circRNA) and PIWI interacting RNA (piRNA), in different type of cancers.

Yan H ，Bu P 《-》

Emerging Role of Non-Coding RNAs in Esophageal Squamous Cell Carcinoma.

Feng Q ，Zhang H ，Yao D ，Chen WD ，Wang YD ... -  《INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES》

Non-coding RNAs derailed: The many influences on the fatty acid reprogramming of cancer.

Non-coding RNAs (NcRNAs), a family of functional RNA molecules that cannot translate into proteins but control specific gene expression programs, have been shown to be implicated in various biological processes, including fatty acid metabolism. Fast-growing tumor cells rewire their fatty acid metabolic circuitry in order to meet the needs of energy storage, membrane proliferation, and the generation of signaling molecules, which is achieved by regulating a variety of key enzymes along with related signaling pathways in fatty acid metabolism. This review presents an update of our knowledge about the regulatory network of ncRNAs-specifically, microRNAs (miRNAs), long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs)-in this metabolic shift and discusses the possibility of ncRNA-based therapeutics being applied to the restoration of cancer-related fatty acid metabolism.

Yu XH ，Wang HF ，Wu JB ，Wang SS ，Tang YJ ，Tang YL ，Liang XH ... -  《-》