Hyperbaric oxygen therapy for maxillary bone radiation-induced injury: A 15-year single-center experience.

Although hyperbaric oxygen therapy (HBOT) is used to treat chronic radiation tissue injury, clinical evidence supporting its use in maxillary bone osteoradionecrosis (ORN) is lacking. Therefore, the purpose of this study was to report our results of collected patient outcomes from a single center's large experience using HBOT to treat maxillary bone ORN. From 1999 to 2015, 21 patients received treatment for maxillary bone ORN at our center. The medical records were retrospectively reviewed for the following variables: age, sex, comorbidities, tumor stage and site, previous surgery, previous radiotherapy or chemoradiation therapy, HBOT data, response to treatment and further management. A positive clinical outcome from HBOT occurred in 85.7% of patients with ORN and was proven radiologically in 14 of 15 patients (93.3%). In 5 patients, reconstructive surgery was required thereafter. Controversy exists regarding the management of ORN of the maxillofacial skeleton. Our large, single-center experience probably supports the efficacy of HBOT for maxillary bone ORN. © 2016 Wiley Periodicals, Inc. Head Neck 39: 275-278, 2017.

Gavriel H ，Eviatar E ，Abu Eta R 《-》

Retrospective audit of the use of the Marx Protocol for prophylactic hyperbaric oxygen therapy in managing patients requiring dental extractions following radiotherapy to the head and neck.

Kaur J ，Hay KD ，Macdonald H ，Rich AM ... -  《-》

Hyperbaric oxygen therapy for late radiation tissue injury.

Bennett MH ，Feldmeier J ，Hampson N ，Smee R ，Milross C ... -  《Cochrane Database of Systematic Reviews》

Hyperbaric oxygen therapy for late radiation tissue injury.

Bennett MH ，Feldmeier J ，Hampson NB ，Smee R ，Milross C ... -  《Cochrane Database of Systematic Reviews》

The influence of hyperbaric oxygen on the outcome of patients treated for osteoradionecrosis: 8 year study.

D'Souza J ，Goru J ，Goru S ，Brown J ，Vaughan ED ，Rogers SN ... -  《INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY》