Incidence of thyroid diseases in Zhejiang Province, China, after 15 years of salt iodization.

Thyroid diseases(TD) can be induced by either deficient or excessive iodine intake. Universal Salt Iodization(USI) program has been implemented in China since 1995, to prevent iodine deficiency disorders (IDD). To evaluate the current conditions of TD and the role of USI, a multi-stage stratified random sampling scheme was used to perform a cross-sectional survey on the incidence of TD among participants in 6600 households in Zhejiang Province, a coastal area in China. Iodine nutrition status of the population was assessed by dietary iodine intake recall and urinary iodine concentration (UIC) of the participants, and TD were diagnosed by thyroid ultrasonography for 15122 participants and for 5873 participants by serum criteria for thyroid function(fT3, fT4, TSH, TRAb, TgAb, TPOAb; see Introduction for abbreviations). The median UIC of the surveyed population was 163μg iodine/L. From the participants 23.2% had UIC<100μg/L which is moderately iodine-deficient according to WHO classification. Diffuse goiter was present in 2.3% of the population and thyroid nodule in 20.9%. The incidence of hyperthyroidism, subclinical hyperthyroidism, hypothyroidism, subclinical hypothyroidism, Graves' disease and chronic lymphocytic thyroiditis was 0.5%, 0.6%, 0.6%, 7.8%, 0.2% and 0.3%, respectively. The proportion of several TD for participants with non-iodized salt intake was higher than that for participants with iodized salt intake.

Gu F ，Ding G ，Lou X ，Wang X ，Mo Z ，Zhu W ，Zhou J ，Mao G ... -  《-》

Iodine Status and Prevalence of Thyroid Disorders After Introduction of Mandatory Universal Salt Iodization for 16 Years in China: A Cross-Sectional Study in 10 Cities.

Shan Z ，Chen L ，Lian X ，Liu C ，Shi B ，Shi L ，Tong N ，Wang S ，Weng J ，Zhao J ，Teng X ，Yu X ，Lai Y ，Wang W ，Li C ，Mao J ，Li Y ，Fan C ，Teng W ... -  《-》

Efficacy and Safety of Long-Term Universal Salt Iodization on Thyroid Disorders: Epidemiological Evidence from 31 Provinces of Mainland China.

Li Y ，Teng D ，Ba J ，Chen B ，Du J ，He L ，Lai X ，Teng X ，Shi X ，Li Y ，Chi H ，Liao E ，Liu C ，Liu L ，Qin G ，Qin Y ，Quan H ，Shi B ，Sun H ，Tang X ，Tong N ，Wang G ，Zhang JA ，Wang Y ，Xue Y ，Yan L ，Yang J ，Yang L ，Yao Y ，Ye Z ，Zhang Q ，Zhang L ，Zhu J ，Zhu M ，Ning G ，Mu Y ，Zhao J ，Shan Z ，Teng W ... -  《-》

An Increase in Consuming Adequately Iodized Salt May Not Be Enough to Rectify Iodine Deficiency in Pregnancy in an Iodine-Sufficient Area of China.

Wang Z ，Zhu W ，Mo Z ，Wang Y ，Mao G ，Wang X ，Lou X ... -  《-》

Iodine nutrition and the prevalence of thyroid disease after salt iodization: a cross-sectional survey in Shanghai, a coastal area in China.

Zou S ，Wu F ，Guo C ，Song J ，Huang C ，Zhu Z ，Yu H ，Guo Y ，Lu X ，Ruan Y ... -  《-》