GENOME-WIDE MAPPING OF COPY NUMBER VARIATIONS IN COMMERCIAL HYBRID PIGS USING A HIGH-DENSITY SNP GENOTYPING ARRAY.

Copy number variations (CNVs) are important forms of structural variation in human and animals and can be considered as a major genetic component of phenotypic diversity. Here we used the Illumina PorcineSNP60 BeadChip V2 and a DLY [Duroc x (Large White x Landrace)] commercial hybrid population to identify 272 CNVs belonging to 165 CNV regions (CNVRs), of which 66 are new. As CNVRs are specific to origin of population, our DLY-specific data is an important complementary to the existing CNV map in the pig genome. Eight CNVRs were selected. for validation by quantitative real-time PCR (qRT-PCR) and the accurate rate was high (87.25%). Gene function analysis suggested that a common CNVR may play an important role in multiple traits, including growth rate and carcass quality.

Zhou LS ，Li J ，Yang J ，Liu CL ，Xie XH ，He YN ，Liu XX ，Xin WS ，Zhang WC ，Ren J ，Ma JW ，Huang LS ... -  《-》

Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs.

Qiu Y ，Ding R ，Zhuang Z ，Wu J ，Yang M ，Zhou S ，Ye Y ，Geng Q ，Xu Z ，Huang S ，Cai G ，Wu Z ，Yang J ... -  《BMC GENOMICS》

Identification of genome-wide copy number variations among diverse pig breeds using SNP genotyping arrays.

Wang J ，Wang H ，Jiang J ，Kang H ，Feng X ，Zhang Q ，Liu JF ... -  《PLoS One》

Identification of genome-wide copy number variations among diverse pig breeds by array CGH.

Li Y ，Mei S ，Zhang X ，Peng X ，Liu G ，Tao H ，Wu H ，Jiang S ，Xiong Y ，Li F ... -  《BMC GENOMICS》

A genome-wide detection of copy number variations using SNP genotyping arrays in swine.

Wang J ，Jiang J ，Fu W ，Jiang L ，Ding X ，Liu JF ，Zhang Q ... -  《BMC GENOMICS》