Long-term outcome of chronic obstructive pulmonary disease patients with acute respiratory failure following intensive care unit discharge in Turkey.

Chronic obstructive pulmonary disease (COPD) remains a globally significant cause of mortality, although COPD mortality varies from country to country, and across different regions within each country. The primary objective of this study was to determine the mortality rates of COPD patients who present with acute respiratory failure (ARF) to a tertiary care referral center in different stages of their follow-up (ICU, in-hospital and after discharge). The secondary objective was to determine factors associated with mortality in this group of patients. Medical records of consecutive COPD patients over a 10-year period were reviewed.The study included 147 patients. Of these, 72 were treated initially with noninvasive positive pressure ventilation (NIPPV), and 12 of these required intubation after NIPPV failed. Therefore, 86 patients were intubated for invasive mechanical ventilation (IMV), while NIPPV was succesful in 60 patients. Survival time was independently associated with advanced age, high APACHE II score, co-morbidity and the need for IMV. The cumulative mortality was 27% in the medical ICU and 31% in hospital following ICU discharge. The mortality rate at 1, 2 and 5 years was 54%, 66% and 84%, respectively. COPD patients admitted to the ICU for ARF have an approximately 70% chance of leaving hospital alive, but half of these may die in the first 6 months after discharge. The risk factors related to mortality were advanced age, high APACHE II score, co-morbidity and IMV requirement.

Ocal S ，Ortac Ersoy E ，Ozturk O ，Hayran M ，Topeli A ，Coplu L ... -  《-》

How do COPD comorbidities affect ICU outcomes?

Ongel EA ，Karakurt Z ，Salturk C ，Takir HB ，Burunsuzoglu B ，Kargin F ，Ekinci GH ，Mocin O ，Gungor G ，Adiguzel N ，Yilmaz A ... -  《International Journal of Chronic Obstructive Pulmonary Disease》

Acute respiratory failure requiring mechanical ventilation in severe chronic obstructive pulmonary disease (COPD).

Gadre SK ，Duggal A ，Mireles-Cabodevila E ，Krishnan S ，Wang XF ，Zell K ，Guzman J ... -  《-》

Performance of noninvasive ventilation in acute respiratory failure in critically ill patients: a prospective, observational, cohort study.

Corrêa TD ，Sanches PR ，de Morais LC ，Scarin FC ，Silva E ，Barbas CS ... -  《BMC Pulmonary Medicine》

Severity of acidosis affects long-term survival in COPD patients with hypoxemia after intensive care unit discharge.

Gungor S ，Kargin F ，Irmak I ，Ciyiltepe F ，Acartürk Tunçay E ，Atagun Guney P ，Aksoy E ，Ocakli B ，Adiguzel N ，Karakurt Z ... -  《International Journal of Chronic Obstructive Pulmonary Disease》