Primary care screening for individuals with impaired glucose metabolism with focus on impaired glucose tolerance.

To evaluate the utility of three short questions (the Skövde Form) combined with a random plasma glucose, and HbA1c as alternative tools for detection of individuals with impaired glucose metabolism (IGM), and particularly impaired glucose tolerance (IGT). Three questions concerning BMI ≥ 25 kg/m(2), heredity for type 2 diabetes, and known hypertension were asked in a random population of 573 individuals. All with two positive answers or one positive answer and a random plasma glucose > 7.2 mmol/l were invited for an oral glucose tolerance test and an HbA1c examination. FINDRISC was completed for comparison. The positive predictive value (PPV) for IGM, using the Skövde Form, was 31% while sensitivity and specificity were 59% and 73%, respectively. Corresponding values for IGT were 11%, 50% and 69%. Using HbA1c ≥ 42 mmol/mol, the PPV for IGM was 64% while sensitivity and specificity were 28% and 97%, respectively. The corresponding values for IGT were 15%, 16% and 94%. The Skövde Form combined with a random plasma glucose may be used as an alternative tool for detection of individuals with IGM and IGT in particular. HbA1c may be used to identify individuals with type 2 diabetes but fails to detect most individuals with prediabetes.

Hellgren MI ，Daka B ，Jansson PA ，Lindblad U ... -  《-》

[HbA1c is not enough in screening for impaired glucose metabolism. Glucose tolerance tests are also needed, as shown in Swedish prospective epidemiological study].

Hellgren M ，Daka B ，Larsson C 《-》

Undetected dysglycaemia common in primary care patients treated for hypertension and/or dyslipidaemia: on the need for a screening strategy in clinical practice. A report from EUROASPIRE IV a registry from the EuroObservational Research Programme of the E

Shahim B ，Gyberg V ，De Bacquer D ，Kotseva K ，De Backer G ，Schnell O ，Tuomilehto J ，Wood D ，Rydén L ... -  《Cardiovascular Diabetology》

Performance of HbA1c versus oral glucose tolerance test (OGTT) as a screening tool to diagnose dysglycemic status in high-risk Thai patients.

Thewjitcharoen Y ，Jones Elizabeth A ，Butadej S ，Nakasatien S ，Chotwanvirat P ，Wanothayaroj E ，Krittiyawong S ，Himathongkam T ，Himathongkam T ... -  《BMC Endocrine Disorders》

Toward targeted prevention: risk factors for prediabetes defined by impaired fasting glucose, impaired glucose tolerance and increased HbA1c in the population-based KORA study from Germany.

Greiner GG ，Emmert-Fees KMF ，Becker J ，Rathmann W ，Thorand B ，Peters A ，Quante AS ，Schwettmann L ，Laxy M ... -  《-》