The Musculature That Drives Active Touch by Vibrissae and Nose in Mice.

Coordinated action of facial muscles during whisking, sniffing, and touching objects is an important component of active sensing in rodents. Accumulating evidence suggests that the anatomical schemes that underlie active sensing are similar across the majority of whisking rodents. Intriguingly, however, muscle architecture in the mystacial pad of the mouse was reported to be different, possessing only one extrinsic vibrissa protracting muscle (M. nasalis) in the rostral part of the snout. In this study, the organization of the muscles that move the nose and the mystacial vibrissae in mice was re-examined and compared with that reported previously in other rodents. We found that muscle distribution within the mystacial pad and around the tip of the nose in mice is isomorphic with that found in other whisking rodents. In particular, in the rostral part of the mouse snout, we describe both protractors and retractors of the vibrissae. Nose movements are controlled by the M. dilator nasi and five subunits of the M. nasolabialis profundus, with involvement of the nasal cartilaginous skeleton as a mediator in the muscular effort translation.

Haidarliu S ，Kleinfeld D ，Deschênes M ，Ahissar E ... -  《-》

Interaction between muscles and fascia in the mystacial pad of whisking rodents.

In whisking rodents, the mystacial pad is supplied with vibrissae and contains a collagenous skeleton that is a part of the snout fascia. The collagenous skeleton is composed of three interconnected layers: superficial, deep spongy mesh and subcapsular fibrous mat. We found that the first two layers contain diverse fascial structures, such as sheets of subcutaneous connective tissue, tendons, ligaments and follicular capsules which transmit muscle efforts to vibrissae and are thus involved in whisking. Subcapsular fibrous mat is built of oriented rostro-caudal wavy fibrils. It maintains spatial arrangement of whisker follicles, provides a quick response to deformation and connects entire mystacial pad to the skull. To move vibrissae, the forces of intrinsic muscles are applied directly to the capsules of the vibrissa follicles, whereas the forces of extrinsic muscles are applied to other parts of the collagenous skeleton, which transmit the forces to the capsules. According to the spatial distribution and anchoring sites of the muscles and fascia, extrinsic muscles provide vibrissa protraction or retraction by pulling the superficial layer of the collagenous skeleton rostral or caudal, respectively. Vibrissae can be also retracted when the efforts of extrinsic muscles are applied to the subcapsular fibrous mat. When the muscles relax, fascial structures return the vibrissae to their resting position. The deep spongy layer encompasses vibrissal follicles providing a uniform distribution of stresses and strains during whisking. In the mystacial pad, fascia is a dominant type of tissue that maintains the integrity of the vibrissa motor plant, translates muscular momentum to the vibrissae, and plays a role in vibrissae movements.

Haidarliu S ，Bagdasarian K ，Sardonicus S ，Ahissar E ... -  《-》

Dorsorostral snout muscles in the rat subserve coordinated movement for whisking and sniffing.

Histochemical examination of the dorsorostral quadrant of the rat snout revealed superficial and deep muscles that are involved in whisking, sniffing, and airflow control. The part of M. nasolabialis profundus that acts as an intrinsic (follicular) muscle to facilitate protraction and translation of the vibrissae is described. An intraturbinate and selected rostral-most nasal muscles that can influence major routs of inspiratory airflow and rhinarial touch through their control of nostril configuration, atrioturbinate and rhinarium position, were revealed.

Haidarliu S ，Golomb D ，Kleinfeld D ，Ahissar E ... -  《-》

Rhythmic whisking by rat: retraction as well as protraction of the vibrissae is under active muscular control.

Berg RW ，Kleinfeld D 《JOURNAL OF NEUROPHYSIOLOGY》

Biomechanics of the vibrissa motor plant in rat: rhythmic whisking consists of triphasic neuromuscular activity.

Hill DN ，Bermejo R ，Zeigler HP ，Kleinfeld D ... -  《-》