The relationship between nicotine cessation and mental disorders in a nationally representative sample.

The objective of this study was to examine the relationship between Axis I and II mental disorders, quality of life, and nicotine dependence cessation in a nationally representative sample. Data came from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), a nationally representative survey of adults in the United States (N = 34,653). People who met DSM-IV criteria for nicotine dependence previously but who had abstained from nicotine in the last year (nicotine cessation) were compared to people currently dependent on nicotine as well as lifetime abstainers using multivariate logistic regression. Outcomes of interest included DSM-IV Axis I and II mental disorders, treatment seeking for mental disorders, and quality of life measures. In adjusted models, individuals who ceased nicotine use in the last year were less likely to have past-year mood [adjusted odds ratio (AOR) = 0.64; 95% confidence interval (CI) 0.50-0.82, p < 0.001] and substance use disorders (AOR = 0.65, 95% CI 0.52-0.82, p < 0.001) compared to those with current nicotine dependence. They were also less likely to have narcissistic and borderline personality disorders. Compared to those with current nicotine dependence, cessation was associated with an improved quality of life, both physically (beta = 1.65; standard error 0.40, p < 0.001) and mentally (beta = 2.17, standard error 0.39, p < 0.001). In conclusion, nicotine dependence cessation was associated with reduced likelihood of several mental disorders and a higher quality of life compared to those with current nicotine dependence. These findings provide further support for public health policy aimed at smoking cessation.

Donald S ，Chartrand H ，Bolton JM 《-》

Nicotine dependence and psychiatric disorders in the United States: results from the national epidemiologic survey on alcohol and related conditions.

Grant BF ，Hasin DS ，Chou SP ，Stinson FS ，Dawson DA ... -  《archives of general psychiatry》

Smoking, nicotine dependence and psychiatric comorbidity--a population-based study including smoking cessation after three years.

John U ，Meyer C ，Rumpf HJ ，Hapke U ... -  《DRUG AND ALCOHOL DEPENDENCE》

The relation between nicotine dependence and suicide attempts in the general population.

Yaworski D ，Robinson J ，Sareen J ，Bolton JM ... -  《-》

Prevalence, characteristics, associated mental disorders and predictors of DSM-IV nicotine dependence.

Focussing on ever-smokers and comparing nicotine-dependent with nondependent subjects, we examined the characteristics, associations of nicotine dependence with other mental disorders as well as predictors of nicotine dependence. Never-smokers were not included in the reference group of the nondependent subjects, but were analyzed as a third group. Data of 1,636 never-smokers and 2,437 ever-smokers (i.e. 1,520 current smokers, 917 former smokers) were taken from the German Transitions in Alcohol Consumption and Smoking Study. Assessments were made using the Composite International Diagnostic Interview. About a third of the ever-smokers met the criteria for nicotine dependence in some point in their lives. Nicotine-dependent smoking was significantly associated with various substance use disorders, affective disorders and anxiety disorders using nondependent smoking as a reference group. Comparing never-smokers and nondependent ever-smokers, significant associations were found for substance use disorders only. Smoking behavior variables, alcohol abuse or dependence and anxiety disorders but not sociodemographic variables and affective disorders were predictors for nicotine dependence. Nicotine-dependent smoking is distinct from smoking alone and nicotine-dependent smokers are a characteristically different subgroup within the smoking population.

Schumann A ，Hapke U ，Meyer C ，Rumpf HJ ，John U ... -  《-》