Ten yr of pediatric heart transplantation: a report from the Pediatric Heart Transplant Study.

The PHTS was founded in 1991 as a not-for-profit organization dedicated to the advancement of the science and treatment of children during listing for and following heart transplantation. Now, 21 yr later, the PHTS has contributed significantly to the field, most notably in the form of outcomes analyses and risk factor assessment, in addition to amassing the most detailed dataset on pediatric heart transplant recipients worldwide. The purpose of this report is to review the last decade of pediatric patients listed for heart transplantation (January 1, 2000-December 31, 2009) and summarize the changes, trends, outcomes, and lessons learned.

Dipchand AI ，Kirk R ，Mahle WT ，Tresler MA ，Naftel DC ，Pahl E ，Miyamoto SD ，Blume E ，Guleserian KJ ，White-Williams C ，Kirklin JK ... -  《-》

Lessons learned from the pediatric heart transplant study.

Hsu DT ，Naftel DC ，Webber SA ，Morrow WR ，Canter CE ，Chinnock RE ，Clark ML ，Kirklin JK ... -  《-》

Comparison of risk factors and outcomes for pediatric patients listed for heart transplantation after bidirectional Glenn and after Fontan: an analysis from the Pediatric Heart Transplant Study.

Patients listed for transplant after the bidirectional Glenn (BDG) may have better outcomes than patients listed after Fontan. This study examined and compared outcomes after listing for BDG and Fontan patients. All patients listed for transplant after the BDG in the Pediatric Heart Transplant Study between January 1993 and December 2008 were evaluated. Comparisons were made with Fontan patients and with a matched cohort of congenital heart disease patients. Competing outcomes analysis and actuarial survival were evaluated for the study populations, including an examination of various risk factors. Competing outcomes analysis for BDG and Fontan patients after listing were similar. There was no difference in actuarial survival after listing or transplant among the 3 cohorts. Mechanical ventilation, United Network of Organ Sharing status, and age were risk factors for death after listing in BDG and Fontan patients, but ventilation at the time of transplant was significant only for the Fontan patients. Mortality was increased in Fontan patients listed < 6 months after surgery compared with patients listed > 6 months after surgery, but no difference was observed in BDG patients. There was a trend toward improved survival after listing for both populations across 3 eras of the study, but this did not reach statistical significance. Outcomes after listing for BDG and Fontan patients are similar. Mechanical ventilation at the time of transplant remains a significant risk factor for death in the Fontan population, as does listing for transplant soon after the Fontan, suggesting that some patients may benefit from transplant instead of Fontan completion.

Kovach JR ，Naftel DC ，Pearce FB ，Tresler MA ，Edens RE ，Shuhaiber JH ，Blume ED ，Fynn-Thompson F ，Kirklin JK ，Zangwill SD ... -  《-》

Outcome of listing for heart transplantation in infants younger than six months: predictors of death and interval to transplantation. The Pediatric Heart Transplantation Study Group.

Morrow WR ，Naftel D ，Chinnock R ，Canter C ，Boucek M ，Zales V ，McGiffin DC ，Kirklin JK ... -  《JOURNAL OF HEART AND LUNG TRANSPLANTATION》

Worldwide thoracic organ transplantation: a report from the UNOS/ISHLT International Registry for Thoracic Organ Transplantation.

Keck BM ，Bennett LE ，Fiol BS ，Dally OP ，Novick RJ ，Hosenpud JD ... -  《-》