Quadriceps and ankle dorsiflexor strength in chronic obstructive pulmonary disease.

Quadriceps strength and size are commonly reduced in chronic obstructive pulmonary disease (COPD). We wished to assess volitional and nonvolitional ankle dorsiflexor strength in COPD. Quadriceps and ankle dorsiflexor strength were measured by maximum voluntary contraction (MVC) and by twitch responses to supramaximal femoral and fibular nerve stimulation. Cross-sectional areas of the tibialis anterior (TA(CSA)) and rectus femoris muscles (RF(CSA)) were measured by ultrasound. Eighteen elderly subjects and 20 COPD patients [mean(SD) %predictedFEV(1) 50(20)%] participated. No significant difference in fat-free mass index, ankle dorsiflexor strength, or TA(CSA) were observed in the presence of reduced quadriceps strength and size in COPD [mean MVC difference: -10.9 kg (95% confidence interval {CI}: -17.1 kg to -4.8 kg, P < 0.01; mean RF(CSA) difference -119 mm(2), 95% CI: -180 mm(2) to -58 mm(2), P < 0.01)]. Ankle dorsiflexor strength is less attenuated than quadriceps strength in COPD patients with moderate airflow obstruction. Direct quadriceps assessment may be more relevant than measurement of lower limb fat-free mass.

Seymour JM ，Ward K ，Raffique A ，Steier JS ，Sidhu PS ，Polkey MI ，Moxham J ，Rafferty GF ... -  《-》

Quadriceps strength assessed by magnetic stimulation of femoral nerve in patients with chronic obstructive pulmonary disease.

Ju CR ，Chen RC 《-》

Ultrasound measurement of rectus femoris cross-sectional area and the relationship with quadriceps strength in COPD.

Seymour JM ，Ward K ，Sidhu PS ，Puthucheary Z ，Steier J ，Jolley CJ ，Rafferty G ，Polkey MI ，Moxham J ... -  《-》

[Investigation of the quadriceps strength in patients with chronic obstructive pulmonary disease].

Ju CR ，Chen RC 《-》

Quadriceps strength predicts mortality in patients with moderate to severe chronic obstructive pulmonary disease.

Swallow EB ，Reyes D ，Hopkinson NS ，Man WD ，Porcher R ，Cetti EJ ，Moore AJ ，Moxham J ，Polkey MI ... -  《-》