Electrocatalytic detection of dopamine in the presence of ascorbic acid and uric acid using single-walled carbon nanotubes modified electrode.

Single-walled carbon nanotubes (SWCNTs) fabricated by sodium dodecyl sulfate (SDS) (f-SWCNTs) modified glassy carbon electrodes (f-SWCNTs/GCE) for the simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA). The f-SWCNTs/GCE displayed very good electrochemical catalytic activities with respect to GCE. The oxidation over-potentials of DA and UA decreased dramatically, and their oxidation peak currents increased significantly at f-SWCNTs/GCE compared to those obtained at the bare GCE. Simultaneously, the oxidation peak currents of AA decreased accordingly. The f-SWCNTs/GCE not only divide the overlapping voltammetric responses of them into individual voltammetric peaks, but also totally eliminate the interference from AA and distinguish DA from UA. The catalytic peak currents obtained from square-wave voltammetry increased linearly with increasing DA concentrations in the range of 5.0×10(-6) to 1.0×10(-4)M with a detection limit of 2.0×10(-8)M (S/N=3). The method was also successfully applied for determination of DA and showed good recovery in some biological fluids.

Li Y ，Du J ，Yang J ，Liu D ，Lu X ... -  《-》

Electrochemically selective determination of dopamine in the presence of ascorbic and uric acids on the surface of the modified Nafion/single wall carbon nanotube/poly(3-methylthiophene) glassy carbon electrodes.

A voltammetric method based on a combination of incorporated Nafion, single-walled carbon nanotubes and poly(3-methylthiophene) film-modified glassy carbon electrode (NF/SWCNT/PMT/GCE) has been successfully developed for selective determination of dopamine (DA) in the ternary mixture of dopamine, ascorbic acid (AA) and uric acid (UA) in 0.1M phosphate buffer solution (PBS) pH 4. It was shown that to detect DA from binary DA-AA mixture, the use of NF/PMT/GCE was sufficient, but to detect DA from ternary DA-AA-UA mixture NF/SWCNT/PMT/GCE was required. The later modified electrode exhibits superior electrocatalytic activity towards AA, DA and UA thanks to synergic effect of NF/SWCNT (combining unique properties of SWCNT such as high specific surface area, electrocatalytic and adsorptive properties, with the cation selectivity of NF). On the surface of NF/SWCNT/PMT/GCE AA, DA, UA were oxidized respectively at distinguishable potentials of 0.15, 0.37 and 0.53 V (vs. Ag/AgCl), to form well-defined and sharp peaks, making possible simultaneous determination of each compound. Also, it has several advantages, such as simple preparation method, high sensitivity, low detection limit and excellent reproducibility. Thus, the proposed NF/SWCNT/PMT/GCE could be advantageously employed for the determination of DA in real pharmaceutical formulations.

Quan do P ，Tuyen do P ，Lam TD ，Tram PT ，Binh NH ，Viet PH ... -  《-》

A novel electrochemical sensor based on carbon nanotubes array for selective detection of dopamine or uric acid.

A novel single-walled carbon nanotubes array-modified glassy carbon electrode (SWCNTs array-GCE) has been fabricated through a simple electrochemical technique. Benefitting from their vertically aligned configuration on the electrode surface, the modified single-walled carbon nanotubes can be used more efficiently in comparison with other modified method. The as-fabricated SWCNTs array-GCE can separate the anodic oxidation potential of dopamine (DA), uric acid (UA) and ascorbic acid (AA) with well-defined peak separation in the presence of each other, and thus employs as a new electrochemical sensor for selective determination of DA and UA. It can make a further improvement of the electrocatalytic ability of the electrode to perform an acetone pretreatment to SWCNTs array-GCE before electrochemical detection, which has been confirmed by atomic force microscope and electrochemical impedance spectroscopic measurements. Especially, unlike other carbon nanotubes-based electrode at which only two redox pairs are observed for dopamine oxidations, a third two-electron oxidation of 5,6-dihydroxyindole to indole-5,6-quinone can be clearly observed at acetone-pretreated SWCNTs array-GCE, showing the excellent electrocatalytic performance of as-fabricated electrode toward dopamine. The practicability of SWCNTs array-GCE was evaluated for the selective detection of DA and UA in real sample solutions of human serum and urine. It revealed acceptable recovery results in the range of 94-104%, indicating that it might be a promising platform for further biosensor development.

Yang Y ，Li M ，Zhu Z 《-》

Electropolymerized film of functionalized thiadiazole on glassy carbon electrode for the simultaneous determination of ascorbic acid, dopamine and uric acid.

Kalimuthu P ，John SA 《-》

Simultaneous electrochemical determination of uric acid, dopamine, and ascorbic acid at single-walled carbon nanohorn modified glassy carbon electrode.

Zhu S ，Li H ，Niu W ，Xu G ... -  《-》