Association of self-reported passive smoking in pregnant women with cotinine level of maternal urine and umbilical cord blood at delivery.

Passive smoking during pregnancy leads to adverse effects on mother and infant. The present investigation was designed to evaluate the association between maternal reported passive smoking with the cotinine concentration of maternal urine and umbilical cord blood at delivery and to determine the accuracy of maternal reporting of exposure to cigarette smoke during pregnancy. This was a cross-sectional study. From the 108 non-smoker pregnant women who were referred for delivery, 54 were passive smokers. Urine samples were collected from the mothers in the delivery room and blood samples after birth were taken from the umbilical cord. Passive smoking was evaluated through questionnaire and cotinine level of urine and umbilical cord blood. The geometric mean cotinine concentration of the maternal urine and the umbilical cord serum were, respectively, 27.4 ± 29.96 ng/mL and 3.71 ± 1.22 ng/mL in the exposed group (P < 0.001) and 0.75 ± 2.29 and 0.40 ± 0.63 in the non-exposed group (P < 0.001). There was a statistically significant correlation between maternal urinary and umbilical cord serum level of cotinine (P < 0.001, r = 0.58). Significant associations were shown between maternal reports of exposure to cigarette smoking with cotinine level of urine (kappa = 96%) and umbilical cord (kappa = 98%) (P < 0.001). This study shows that the pregnant woman's report of passive smoking during pregnancy in Iran is accurate. The questionnaire is an appropriate method to evaluate smoke exposure and could replace cotinine measurement.

Baheiraei A ，Banihosseini SZ ，Heshmat R ，Mota A ，Mohsenifar A ... -  《-》

Effect of passive smoking using maternal and neonatal salivary cotinine measurements.

Sachiyo K ，Kumiko A ，Keiko N ，Kaori K ，Sonomi O ... -  《-》

[Estimation of passive smoking during pregnancy by cotinine measurement and its effect on fetal growth].

Ueda Y ，Morikawa H ，Funakoshi T ，Kobayashi A ，Yamasaki A ，Takeuchi K ，Mochizuki M ，Jimbo T ，Sato A ... -  《-》

The relationship between self-reported tobacco exposure and cotinines in urine and blood for pregnant women.

Chiu HT ，Isaac Wu HD ，Kuo HW 《SCIENCE OF THE TOTAL ENVIRONMENT》

Comparison of urinary and plasma cotinine levels during the three trimesters of pregnancy.

Wu FY ，Chiu HT ，Wu HD ，Lin CJ ，Lai JS ，Kuo HW ... -  《-》