Preventive chemotherapy in human helminthiasis: theoretical and operational aspects.

Preventive chemotherapy (PC), the large-scale distribution of anthelminthic drugs to population groups at risk, is the core intervention recommended by the WHO for reducing morbidity and transmission of the four main helminth infections, namely lymphatic filariasis, onchocerciasis, schistosomiasis and soil-transmitted helminthiasis. The strategy is widely implemented worldwide but its general theoretical foundations have not been described so far in a comprehensive and cohesive manner. Starting from the information available on the biological and epidemiological characteristics of helminth infections, as well as from the experience generated by disease control and elimination interventions across the world, we extrapolate the fundamentals and synthesise the principles that regulate PC and justify its implementation as a sound and essential public health intervention. The outline of the theoretical aspects of PC contributes to a thorough understanding of the different facets of this strategy and helps comprehend opportunities and limits of control and elimination interventions directed against helminth infections.

Gabrielli AF ，Montresor A ，Chitsulo L ，Engels D ，Savioli L ... -  《-》

Comment on: preventive chemotherapy in human helminthiasis: theoretical and operational aspects.

Coles GC 《-》

Prevalence of soil-transmitted helminth infections, schistosomiasis, and lymphatic filariasis before and after preventive chemotherapy initiation in the Philippines: A systematic review and meta-analysis.

Delos Trinos JPCR ，Wulandari LPL ，Clarke N ，Belizario V Jr ，Kaldor J ，Nery SV ... -  《PLoS Neglected Tropical Diseases》

Preventive chemotherapy for helminth diseases: progress report, 2014.

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Nigeria's war on terror: fighting dracunculiasis, onchocerciasis, lymphatic filariasis, and schistosomiasis at the grassroots.

Njepuome NA ，Hopkins DR ，Richards FO Jr ，Anagbogu IN ，Pearce PO ，Jibril MM ，Okoronkwo C ，Sofola OT ，Withers PC Jr ，Ruiz-Tiben E ，Miri ES ，Eigege A ，Emukah EC ，Nwobi BC ，Jiya JY ... -  《-》