Postinfectious irritable bowel syndrome: follow-up of a patient cohort of confirmed cases of bacterial infection with Salmonella or Campylobacter.

Gastrointestinal infections have been proposed to predict subsequent irritable bowel syndrome (IBS) but large-scale infectious events are rare and long-term data are missing. We identified 576 individuals with a Salmonella or Campylobacter infection between 2000 and 2009 that were followed by a short postal questionnaire asking for the presence of current symptoms in 2010. In case of agreement (n = 90), an extended postinfectious (PI)-IBS questionnaire was mailed including the Hospital Anxiety Depression Scale and the Patient Health Questionnaire. A total of 189 patients reported back (36%); 98 had a Salmonella and 91 had a Campylobacter infection, of which 56 reported persistent symptoms (9.7% of the initial sample). Fifty-one patients returned the PI-IBS questionnaire. Of 48 patients with complete data, 15 reported no or mild symptoms of abdominal pain or discomfort while 17 had moderate and 16 severe symptoms. Twenty-two met Rome IBS criteria, 14 (29%) reported GI symptoms before the infection. Patients with moderate and/or severe PI-IBS symptoms were significantly more often females, were more often infected by Salmonella than by Campylobacter, had more severe symptoms during the initial infection, and had more often GI symptoms prior to the infection. They reported higher anxiety, depression, and somatisation scores, but were not different with respect to acute stool habits. Nearly 10% of patients with an intestinal bacterial infection report postinfectious symptoms up to 10 years after the infectious event. They represent a clinically important population with high psychiatric comorbidity and somatic symptom burden.

Schwille-Kiuntke J ，Enck P ，Zendler C ，Krieg M ，Polster AV ，Klosterhalfen S ，Autenrieth IB ，Zipfel S ，Frick JS ... -  《-》

To "lump" or to "split" the functional somatic syndromes: can infectious and emotional risk factors differentiate between the onset of chronic fatigue syndrome and irritable bowel syndrome?

Moss-Morris R ，Spence M 《-》

Gastrointestinal-specific anxiety: an important factor for severity of GI symptoms and quality of life in IBS.

Jerndal P ，Ringström G ，Agerforz P ，Karpefors M ，Akkermans LM ，Bayati A ，Simrén M ... -  《-》

Comorbidity and use of health-care services among irritable bowel syndrome sufferers.

Hillilä MT ，Siivola MT ，Färkkilä MA 《-》

The clinical course of postinfectious irritable bowel syndrome: a five-year follow-up study.

Jung IS ，Kim HS ，Park H ，Lee SI ... -  《-》