Cytotoxic tirucallane C26 triterpenoids from the stem barks of Aphanamixis grandifolia.

Five tirucallane type C(26) triterpenoids, accompanied by two known compounds, 3α-hydroxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone and 3-oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, were isolated from the stem barks of Aphanamixis grandifolia. Their structures were established mainly by means of a combination of 1D and 2D NMR spectroscopic and mass spectrometry techniques as 3α-hydroxyl-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, 3α-hydroxy-21β-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, 3-oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, 3-oxo-21β-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, and 3-oxo-21α-ethoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone. All isolates were in vitro evaluated for their cytotoxic activities against five tumor cell lines (MCF-7, HeLa, HepG2, SGC-7901 and BGC-823).

Zhang Y ，Wang J ，Wei D ，Wang X ，Luo J ，Luo J ，Kong L ... -  《-》

Tirucallane-type alkaloids from the bark of Dysoxylum laxiracemosum.

Zhang XY ，Li Y ，Wang YY ，Cai XH ，Feng T ，Luo XD ... -  《-》

Tirucallane triterpenoids from Cornus walteri.

Kim KH ，Choi SU ，Kim YC ，Lee KR ... -  《-》

Triterpenoids from Aglaia abbreviata and their cytotoxic activities.

Zhang F ，Wang JS ，Gu YC ，Kong LY ... -  《-》

Cytotoxic triterpenoid alkaloids from Buxus microphylla.

Yan YX ，Hu XD ，Chen JC ，Sun Y ，Zhang XM ，Qing C ，Qiu MH ... -  《-》