Incidence of nonmelanoma skin cancer after human organ transplantation: single-center experience in Hungary.

There is increasing evidence that nonmelanoma skin cancers (NMSCs) are the most frequently observed tumors in transplant recipients. The incidence of posttransplantation NMSC was determined using our dermatologic screening program. Included in the study were 116 white adults (70 men and 46 women; median age, 49.3 years) who had undergone kidney or combined kidney-pancreas transplantation, with follow-up from September 2008 to December 2009. All patients underwent a full skin examination for NMSC, and completed a standardized questionnaire. Screening resulted in detection of 16 NMSCs in 11 patients out of 116 (9.5%). Lesions were equally distributed by sex, and were detected at a median of 4.1 years posttransplantation. Histologic analysis verified 13 basal cell carcinomas and 3 squamous cell carcinomas (ratio, 4:1). The incidence of NMSC was significantly greater in patients who received cyclosporine immunosuppression therapy (16 vs 1; P < .05), had experienced 2 or more painful sunburns before transplantation (10 vs 11), or worked outdoors (10 vs 11). These data indicate the relevance of skin cancer surveillance in transplant recipients. Our results correspond to international statistics except for the ratio of basal cell carcinoma to squamous cell carcinoma. Further studies are needed to elucidate the reasons for this difference.

Fekecs T ，Kádár Z ，Battyáni Z ，Kalmár-Nagy K ，Szakály P ，Horváth OP ，Wéber G ，Ferencz A ... -  《-》

Incidence and clinical predictors of a subsequent nonmelanoma skin cancer in solid organ transplant recipients with a first nonmelanoma skin cancer: a multicenter cohort study.

Tessari G ，Naldi L ，Boschiero L ，Nacchia F ，Fior F ，Forni A ，Rugiu C ，Faggian G ，Sassi F ，Gotti E ，Fiocchi R ，Talamini G ，Girolomoni G ... -  《-》

[Clinical study of non-melanoma skin cancer following human organ transplantation].

Fekecs T ，Kádár Z ，Battyáni Z ，Kalmár-Nagy K ，Szakály P ，Wéber G ，Horváth OP ，Ferencz A ... -  《-》

First and subsequent nonmelanoma skin cancers: incidence and predictors in a population of New Zealand renal transplant recipients.

Mackenzie KA ，Wells JE ，Lynn KL ，Simcock JW ，Robinson BA ，Roake JA ，Currie MJ ... -  《-》

Changes in oxidative stress in patients screened for skin cancer after solid-organ transplantation.

Fekecs T ，Kádár Z ，Battyáni Z ，Kalmár-Nagy K ，Szakály P ，Horváth OP ，Wéber G ，Ferencz A ... -  《-》