Prevalence and associated factors of sexual problems after early-stage breast cancer treatment: results of a French exploratory survey.

The objective of this study was to assess the prevalence and associated factors of sexual activity, sexual problems or sexual satisfaction in French early-stage breast cancer survivors (BCS). Eight hundred and fifty eligible, post-treatment (6 months-5 years) female patients, aged 18-70 years, randomly selected from a consultation list, were invited to fill in questionnaires exploring quality of life (EORTC QLQ-C30 and QLQ-BR23), body image scale, and sexuality (Sexual Activity Questionnaire-SAQ; Relationship and Sexuality Scale; French Sexual Behaviour Survey-CSF). Fifty-three percent of BCS agreed to participate. Participating women (n=378) were younger, more often premenopausal at diagnosis and with a more recent diagnosis than non-respondents. The prevalence of sexual problems was significantly higher in BCS compared with adjusted data from a French female representative sample (p<0.0001). In logistic regression, no sexual activity (R(2) =0.37) or sexual dissatisfaction (R(2) =0.28) were associated with the feeling of emotional separation in the couple or of partner's fear of sexual intercourse, lower emotional functioning, poorer body image, or co-morbidities. In sexually active women (71% of respondents), lower frequency of sexual activity (R(2) =0.26), lower sexual pleasure (R(2) =0.22), or higher sexual discomfort (R(2) =0.22) were associated with the feeling of emotional separation in the couple or of partner's fear of sexual intercourse, lower emotional functioning, age (>50 years), nausea, or insomnia (all Hosmer-Lemeshow tests: p=NS). Psychological factors including the perception of the couple relationship appeared prominent in BCS women's experience of sexual problems.

Brédart A ，Dolbeault S ，Savignoni A ，Besancenet C ，This P ，Giami A ，Michaels S ，Flahault C ，Falcou MC ，Asselain B ，Copel L ... -  《-》

Quality of life and sexual functioning in young women with early-stage breast cancer 1 year after lumpectomy.

The breast cancer (BC) and its treatment (mastectomy, radiotherapy, and chemotherapy) have considerable psychosexual impacts on women's life. This study evaluated sexual functioning, quality of life, and self-esteem in young women with early-stage BC. A total of 186 women with stage I or II BC and 204 age-matched controls aged 25-45 years were recruited. To be eligible, patients had to be disease-free and sexually active. They also had to have undergone lumpectomy at least 1 year previously and have completed chemotherapy and/or radiotherapy. Subjects completed Female Sexual Function Index, Short Form-36 Health Survey, and Rosenberg Self-Esteem questionnaire. Serum sex hormones were also measured in all subjects. Of BC patients, 57% experienced lubrication disorder followed by satisfaction disorder in 53.8%, desire disorder in 42.5%, and arousal disorder in 37.0% (all patients vs. healthy controls <0.01). Hormone-treated patients were more likely to report sexual dysfunctions (p = 0.006). The radiotherapy + chemotherapy + hormone therapy was associated with an about sixfold increased risk of lubrication and satisfaction disorders (adjusted odds ratios = 6.4, 95%CI = 4.6-12.6, and adjusted odds ratios = 5.7, 95%CI = 3.4-11.4, respectively). Cancer patients had lower scores for all components of the Short Form-36 Health Survey, except for pain. Levels of self-esteem did not differ significantly between the two groups. Young lumpectomized BC women reported a marked impairment in sexual functioning and quality of life.

Safarinejad MR ，Shafiei N ，Safarinejad S 《-》

Body image and sexual problems in young women with breast cancer.

Fobair P ，Stewart SL ，Chang S ，D'Onofrio C ，Banks PJ ，Bloom JR ... -  《-》

[Study of sexuality among Tunisian women in remission from non-metastatic breast cancer, about 100 women].

Zaied S ，Ben Fatma L ，Laadhari A ，Boudegga MZ ，Hochlef M ，Chabchoub I ，Ezzairi F ，Gharbi O ，Gaha L ，Ben Ahmed S ... -  《-》

The effect of a sexual life reframing program on marital intimacy, body image, and sexual function among breast cancer survivors.

Jun EY ，Kim S ，Chang SB ，Oh K ，Kang HS ，Kang SS ... -  《-》