Event-related components of the punishment and reward sensitivity.

The present study investigated the properties of feedback-related negativity (FRN) and P3 component of the event-related potentials (ERPs) and their neural sources localization as neurocognitive correlates of the behavioural inhibition and behavioural activation systems (BIS/BAS). The association between BIS/BAS function and anterior cortical asymmetry was tested. Fifty right-handed women were investigated with 30-channel recordings during an instrumental Go/No-Go learning task. ERPs were elicited to feedback signals indicating monetary losses and monetary gains. Learning performance, FRN, and P3 amplitude and latency measures were calculated and related to BIS and BAS measures by means of ANOVA and correlation analysis. The neural sources of FRN and P3 components of the ERPs were estimated using LORETA software. A resting EEG-alpha-power (8-13Hz) asymmetry measure was obtained. High levels of Reward Responsiveness (RR), a first order factor of the BAS, were associated with shorter RTs and enhanced positive feelings. The FRN was larger to signals indicating monetary Loss as compared to monetary Gain and enhanced with higher BIS and individual learning ability. Higher RR scores were related to greater left-sided resting frontal cortical asymmetry associated with approach orientation. High-RR subjects, as compared to Low-RR ones, had a smaller P3 amplitude for Go/Loss signals. The P3 latency to No-Go/Gain signals was the best positive predictor of RR. LORETA source localization for the FRN component displayed significantly higher brain electrical activity in left-fusiform gyrus and right superior temporal gyrus to monetary Loss in comparison to monetary Gain after incorrect No-Go responses. For the P3 wave, the monetary Loss produced significantly higher activations in the left superior parietal lobule, right postcentral gyrus, and in the ACC. The FRN was sensitive to cues of punishment and higher BIS was uniquely related to a larger FRN amplitude on No-Go/Loss trials, linking BIS with conflict monitoring and sensitivity to No-Go cues. Furthermore, the significant interaction found between BIS and RR on FRN amplitude together with the findings linking High-RR levels with shorter RTs, smaller P3 amplitudes and enhanced positive feelings are in line with the hypothesis that both BIS and BAS have the potential to influence punishment-mediated and reward-mediated behaviour. Results open up new perspectives for future investigations on the relationship between BIS/BAS measures and ERP components to monetary reward during learning.

De Pascalis V ，Varriale V ，D'Antuono L 《-》

FRN and P300 ERP effect modulation in response to feedback sensitivity: the contribution of punishment-reward system (BIS/BAS) and behaviour identification of action.

Balconi M ，Crivelli D 《-》

Baseline EEG theta/beta ratio and punishment sensitivity as biomarkers for feedback-related negativity (FRN) and risk-taking.

Feedback-related negativity (FRN) is associated with reinforcement learning and punishment sensitivity. Furthermore, reinforcement learning proficiency can be predicted from pre-task baseline EEG theta/beta ratio. In this study it was examined whether there was a relation between baseline theta/beta ratio in rest and FRN amplitude during a gambling task, and if such a correlation would be related to theta activity or to beta activity. Baseline EEG and a self-report measure of punishment sensitivity (BIS) were obtained from 52 healthy volunteers. FRN was recorded during a gambling task. FRN amplitude was negatively correlated with theta/beta ratio in high BIS individuals. Furthermore, source localization indicated that baseline theta activity generated in the anterior cingulate cortex (ACC) accounted for this correlation. For low BIS individuals no correlation was found. An association between high baseline theta/beta ratio with low amplitude FRN and high risk-taking can be found in individuals who score sufficiently high on the BIS scale. This relationship is carried mostly by baseline theta activity, but not by beta activity. This link between baseline brain activity, self-report measures and feedback processing may contribute to further understanding the biological basis of conditions that are accompanied by abnormal theta/beta ratio and reward processing, such as attention deficit hyper activity disorder (ADHD).

Massar SA ，Rossi V ，Schutter DJ ，Kenemans JL ... -  《-》

An electrophysiological monetary incentive delay (e-MID) task: a way to decompose the different components of neural response to positive and negative monetary reinforcement.

The ability to anticipate and then secure future rewards and avoid future punishments by responding effectively to environmental demands is at the core of successful decision making. Disruptions to these processes have been shown to be implicated in a number of psychiatric conditions. In the current paper we use the electrophysiological monetary incentive delay task (e-MID) to decompose the neural response to (i) reinforcement anticipation, (ii) reinforcement-contingent target processing and (iii) reinforcement-related feedback. Thirty-eight adolescents and young adults performed an ERP-based analogue of the monetary incentive delay task. ERP components previously associated with motivationally salient cue (cue-P3 and contingent negative variation, CNV), target (P3) and feedback (success vs. failure; feedback-related negativity; FRN and the late positive potential; LPP) stimuli were examined. Response times were shorter and less variable in the monetary gain and loss conditions. Distinctive ERP components were observed for each phase of reinforcement processing. First, cue-P3 was enhanced to monetary gain cues. Predicted alterations in cue-P3 following monetary loss cues and the CNV following cues of either monetary loss or gain were not observed. Target P3 was enhanced in both incentive conditions. The FRN was greater following monetary loss feedback. LPP amplitude was enhanced following feedback denoting monetary gain and the avoidance of monetary loss. Although behaviourally the effects of monetary loss and gain were similar, the e-MID task differentiated neural processing in terms of anticipation and feedback-related brain potentials. The e-MID task and the results of the current study provide a valuable complement to fMRI-based approaches to studying normal and abnormal brain correlates of reinforcement processing.

Broyd SJ ，Richards HJ ，Helps SK ，Chronaki G ，Bamford S ，Sonuga-Barke EJ ... -  《-》

Can event-related potentials serve as neural markers for wins, losses, and near-wins in a gambling task? A principal components analysis.

Originally, the feedback related negativity (FRN) event-related potential (ERP) component was considered to be a robust neural correlate of non-reward/punishment processing, with greater negative deflections observed following unfavourable outcomes. More recently, it has been suggested that this component is better conceptualised as a positive deflection following rewarding outcomes. The current study sought to elucidate the nature of the FRN, as well as another component associated with incentive-value processing, the P3b, through application of a spatiotemporal principal components analysis (PCA). Seventeen healthy controls played a computer electronic gaming machine (EGM) task and received feedback on credits won or lost on each trial, and ERPs were recorded. The distribution of reward/non-reward outcomes closely matched that of a real EGM, with frequent losses, and infrequent wins and near-wins. The PCA revealed that feedback elicited both a frontally maximal negative deflection to losses, and a positive deflection to wins (which was also sensitive to reward magnitude), implying that the neural generator/s of the FRN are differentially activated following these outcomes. As expected, greater P3b amplitudes were found for wins compared to losses. Interestingly, near-wins elicited significantly smaller FRN amplitudes than losses (with no differences in P3b amplitude), and may contribute to the maintenance of gambling behaviours on EGMs. The results of the current study are integrated into a response profile of healthy controls to outcomes of varying incentive value. This may provide a foundation for the future examination of individuals who exhibit abnormalities in reward/punishment processing, such as problem gamblers.

Lole L ，Gonsalvez CJ ，Barry RJ ，De Blasio FM ... -  《-》