The impact of renal function on the long-term clinical course of patients who underwent percutaneous coronary intervention.

To determine the impact of the level of kidney function on the extended (>5 years) long-term clinical course of patients undergoing percutaneous coronary intervention (PCI). Chronic kidney disease (CKD) has been significantly associated with an increased in-hospital and 1-year mortality following PCI. In this single-centre retrospective study, glomerular filtration rate (GFR) at baseline was estimated in 371 patients not on dialysis, who underwent successful PCI between mid-1995 and mid-1999. Baseline demographic and angiographic characteristics, and long-term major adverse cardiac events and symptoms were compared for patients with GFR > or =60 ml/min/1.73 m(2) (normal or mildly impaired renal function) and GFR > or = 60 ml/ min/1.73 m(2) (CKD). The independent effect of GFR, modelled both as a categorical and a continuous variable, on long-term clinical outcomes was also investigated using multivariate Cox regression analysis. Nine-year all-cause and cardiac mortality rates were significantly higher in the CKD group (45.9% vs. 10.6%, P < 0.0001 and 35.4% vs. 7.1%, P < 0.0001 respectively), while there was no difference in the repeat revascularization (P = 0.27) and nonfatal Q-wave myocardial infarction (P = 0.74) rates. Multivariate analysis demonstrated an independent impact of the level of GFR on long-term mortality; adjusted 9-year all-cause and cardiac mortality increased by approximately 16% and 11%, respectively for a decrease of GFR from 120 to 60 ml/min/1.73 m(2) and by approximately 14% and 9%, respectively for a decrease of GFR from 60 to 30 ml/min/1.73 m(2). The level of renal function is a strong determinant of long-term all-cause and cardiac mortality after successful PCI.

Papafaklis MI ，Naka KK ，Papamichael ND ，Kolios G ，Sioros L ，Sclerou V ，Katsouras CS ，Michalis LK ... -  《CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS》

The interaction of vascular inflammation and chronic kidney disease for the prediction of long-term death after percutaneous coronary intervention.

Fathi RB ，Gurm HS ，Chew DP ，Gupta R ，Bhatt DL ，Ellis SG ... -  《-》

Relationship between severity of renal impairment and 2-year outcomes after sirolimus-eluting stent implantation.

Ota T ，Umeda H ，Yokota S ，Miyata S ，Takamura A ，Sugino S ，Hayashi K ，Ishiki R ，Takeichi Y ，Iwase M ，Inagaki H ，Murohara T ... -  《-》

Impact of chronic kidney disease on prognosis of patients with diabetes mellitus treated with percutaneous coronary intervention.

Nikolsky E ，Mehran R ，Turcot D ，Aymong ED ，Mintz GS ，Lasic Z ，Lansky AJ ，Tsounias E ，Moses JW ，Stone GW ，Leon MB ，Dangas GD ... -  《AMERICAN JOURNAL OF CARDIOLOGY》

Short- and long-term clinical outcomes of coronary drug-eluting stent recipients presenting with chronic renal disease.

Mishkel GJ ，Varghese JJ ，Moore AL ，Aguirre F ，Markwell SJ ，Shelton M ... -  《-》