Correlation of activation sizes between lateral geniculate nucleus and primary visual cortex in humans.

It is well established that the lateral geniculate nucleus (LGN) and the primary visual cortex (V1) are retinotopically organized. This similarity is expected to reflect a correlation of activation sizes between V1 and LGN during visual stimulation. However, it is a challenge to determine this functional correlation experimentally in the human brain using most neuroimaging techniques due to their low sensitivity for detecting small LGN activation in the thalamus. The purpose of this study was to examine the functional correlation of activation sizes between LGN and V1 during fullfield and hemifield visual stimulation using a large visual field and high-resolution fMRI technique at 4 Tesla. The correlation was determined by comparing the V1 and LGN activation size ratios between the left and right hemispheres of the same subjects. The results reveal 1) a linear correlation of functional activation size ratio between LGN and V1 with a correlation coefficient of 0.96, and 2) the capability of fMRI for quantifying spatial correlation between cortical and subcortical activation. Magn Reson Med 45:202-205, 2001.

Chen W ，Zhu XH 《MAGNETIC RESONANCE IN MEDICINE》

Mapping of lateral geniculate nucleus activation during visual stimulation in human brain using fMRI.

Chen W ，Kato T ，Zhu XH ，Strupp J ，Ogawa S ，Ugurbil K ... -  《MAGNETIC RESONANCE IN MEDICINE》

Retinotopic mapping of lateral geniculate nucleus in humans using functional magnetic resonance imaging.

Chen W ，Zhu XH ，Thulborn KR ，Ugurbil K ... -  《-》

Effects of voxel size on detection of lateral geniculate nucleus activation in functional magnetic resonance imaging.

Miki A ，Liu CS ，Liu GT 《JAPANESE JOURNAL OF OPHTHALMOLOGY》

Human primary visual cortex and lateral geniculate nucleus activation during visual imagery.

Chen W ，Kato T ，Zhu XH ，Ogawa S ，Tank DW ，Ugurbil K ... -  《NEUROREPORT》