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Scientific Data is a peer-reviewed, open-access journal for descriptions of scientifically valuable datasets, and research that advances the sharing and reuse of scientific data. Read our key principles ▸ Scientific Data welcomes submissions from a broad range of research disciplines, including descriptions of big or small datasets, from major consortiums to single research groups. Scientific Data primarily publishes Data Descriptors, a new type of publication that focuses on helping others reuse data, and crediting those who share. Read our aims & scope ▸ All content is hosted on nature.com – the destination of millions of scientists globally every month. Publications are indexed in PubMed, MEDLINE, Google Scholar and Clarivate's Web of Science, and are automatically deposited into PubMed Central.
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Genomic Reference Resource for African Cattle: Genome Sequences and High-Density Array Variants.
The diversity in genome resources is fundamental to designing genomic strategies for local breed improvement and utilisation. These resources also support gene discovery and enhance our understanding of the mechanisms of resilience with applications beyond local breeds. Here, we report the genome sequences of 555 cattle (208 of which comprise new data) and high-density (HD) array genotyping of 1,082 samples (537 new samples) from indigenous African cattle populations. The new sequences have an average genome coverage of ~30X, three times higher than the average (~10X) of the over 300 sequences already in the public domain. Following variant quality checks, we identified approximately 32.3 million sequence variants and 661,943 HD autosomal variants mapped to the Bos taurus reference genome (ARS-UCD1.2). The new datasets were generated as part of the Centre for Tropical Livestock Genetics and Health (CTLGH) Genomic Reference Resource for African Cattle (GRRFAC) initiative, which aspires to facilitate the generation of this livestock resource and hopes for its utilisation for complete indigenous breed characterisation and sustainable global livestock improvement.
被引量:- 发表:1970