
自引率: 2.9%
被引量: 312599
通过率: 暂无数据
审稿周期: 5.01
版面费用: 3690
国人发稿量: 1178
投稿须知/期刊简介:
Nature Communications is an open access journal that publishes high-quality research from all areas of the natural sciences and has an Impact Factor of 11.470 according to the 2014 Journal Citation Reports®Science Edition (Thomson Reuters, 2015). This places Nature Communications third among all multidisciplinary science primary research journals, with Nature being first. Papers published by the journal represent important advances of significance to specialists within each field.Manuscript submissionsPlease see our brief guide to manuscript submission in PDF format for an overview of key information on submitting primary research for publication in Nature Communications.The guide to publication policies of the Nature journals (including the guide for referees), is also available inPDF format.投稿需知:http://www.nature.com/ncomms/authors/submit.htmlAims and scope of the journalNature Communications is an open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, physical, chemical and Earth sciences. Papers published by the journal represent important advances of significance to specialists within each field.The scope of the journal reflects Nature Publishing Group''''''''''''''''s core strength in the natural sciences, and includes areas in which Nature research journals serve to publish the most outstanding community-focused research papers. In addition, Nature Communications encourages submissions in fields that aren''''''''''''''''t represented by a dedicated Nature research journal; for example developmental biology, plant sciences, microbiology, ecology and evolution, palaeontology and astronomy. The editors particularly welcome submissions from cross-disciplinary fields, including biophysics, bioengineering, chemical physics and environmental science, although no area is excluded from consideration. In all cases, papers published inNature Communications will be of high quality, without necessarily having the scientific reach of papers published in Nature and the Nature research journals.Nature Communications is committed to providing an efficient service for both authors and readers. A streamlined peer-review system, together with the support of an Editorial Advisory Panel, allows a team of independent editors to make rapid and fair publication decisions. Prompt dissemination of accepted papers to Nature Publishing Group''''''''''''''''s wide readership and beyond is achieved through a programme of continuous online publication. Published manuscripts are enhanced by innovative web technologies, including interactive browsing and efficient data- and text-mining.Nature Communications is editorially independent, and its editors will make their own decisions independently of the other Nature journals. It is for authors alone to decide where to submit their manuscripts. Nature will continue to publish the most significant advances in science and the Nature research journals will publish landmark papers of interest to their specific communities. Nature Communications will publish high-quality papers from all areas of science that represent important advances within specific scientific disciplines, but that might not necessarily have the scientific reach of papers published in Nature and the Nature research journals. For papers that could satisfy the scope of more than one Nature journal, the choice of which journal to submit to first lies with the authors.If a paper is rejected from one Nature journal, the authors can use an automated manuscript transfer service to submit the paper to Nature Communications via a link sent to them by the editor handling the manuscript. Authors should note that referees'''''''''''''''''''''''''''''''' comments (including any confidential comments to the editor) and identities are transferred to the editor of the second journal along with the manuscript. The journal editors will take the previous reviews into account when making their decision, although in some cases the editors may choose to take advice from additional referees. Alternatively, authors may choose to request a fresh review, in which case they should not use the automated transfer link, and the editors will evaluate the paper without reference to the previous review process. Nature Communications differs from other Nature journals in that editors occasionally seek advice from members of an Editorial Advisory Panel in deciding whether to review manuscripts. Further information about the Editorial Advisory Panel can be found in the Guide to Authors.
期刊描述简介:
Nature Communications is an open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, physical, chemical and Earth sciences. Papers published by the journal represent important advances of significance to specialists within each field. The scope of the journal reflects Nature Publishing Group''''''''s core strength in the natural sciences, and includes areas in which Nature research journals serve to publish the most outstanding community-focused research papers. In addition, Nature Communications encourages submissions in fields that aren''''''''t represented by a dedicated Nature research journal; for example developmental biology, plant sciences, microbiology, ecology and evolution, palaeontology and astronomy. The editors particularly welcome submissions from cross-disciplinary fields, including biophysics, bioengineering, chemical physics and environmental science, although no area is excluded from consideration. In all cases, papers published inNature Communications will be of high quality, without necessarily having the scientific reach of papers published in Nature and the Nature research journals. Nature Communications is committed to providing an efficient service for both authors and readers. A streamlined peer-review system, together with the support of an Editorial Advisory Panel, allows a team of independent editors to make rapid and fair publication decisions. Prompt dissemination of accepted papers to Nature Publishing Group''''''''s wide readership and beyond is achieved through a programme of continuous online publication. Published manuscripts are enhanced by innovative web technologies, including interactive browsing and efficient data- and text-mining. Nature Communications is editorially independent, and its editors will make their own decisions independently of the other Nature journals. It is for authors alone to decide where to submit their manuscripts. Nature will continue to publish the most significant advances in science and the Nature research journals will publish landmark papers of interest to their specific communities. Nature Communications will publish high-quality papers from all areas of science that represent important advances within specific scientific disciplines, but that might not necessarily have the scientific reach of papers published in Nature and the Nature research journals. For papers that could satisfy the scope of more than one Nature journal, the choice of which journal to submit to first lies with the authors. If a paper is rejected from one Nature journal, the authors can use an automated manuscript transfer service to submit the paper to Nature Communications via a link sent to them by the editor handling the manuscript. Authors should note that referees'''''''''''''''' comments (including any confidential comments to the editor) and identities are transferred to the editor of the second journal along with the manuscript. The journal editors will take the previous reviews into account when making their decision, although in some cases the editors may choose to take advice from additional referees. Alternatively, authors may choose to request a fresh review, in which case they should not use the automated transfer link, and the editors will evaluate the paper without reference to the previous review process. Nature Communications differs from other Nature journals in that editors occasionally seek advice from members of an Editorial Advisory Panel in deciding whether to review manuscripts. Further information about the Editorial Advisory Panel can be found in the Guide to Authors.
-
Global genetic diversity, introgression, and evolutionary adaptation of indicine cattle revealed by whole genome sequencing.
Indicine cattle, also referred to as zebu (Bos taurus indicus), play a central role in pastoral communities across a wide range of agro-ecosystems, from extremely hot semiarid regions to hot humid tropical regions. However, their adaptive genetic changes following their dispersal into East Asia from the Indian subcontinent have remained poorly documented. Here, we characterize their global genetic diversity using high-quality whole-genome sequencing data from 354 indicine cattle of 57 breeds/populations, including major indicine phylogeographic groups worldwide. We reveal their probable migration into East Asia was along a coastal route rather than inland routes and we detected introgression from other bovine species. Genomic regions carrying morphology-, immune-, and heat-tolerance-related genes underwent divergent selection according to Asian agro-ecologies. We identify distinct sets of loci that contain promising candidate variants for adaptation to hot semi-arid and hot humid tropical ecosystems. Our results indicate that the rapid and successful adaptation of East Asian indicine cattle to hot humid environments was promoted by localized introgression from banteng and/or gaur. Our findings provide insights into the history and environmental adaptation of indicine cattle.
被引量:6 发表:1970
-
Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle.
Inbred animals were historically chosen for genome analysis to circumvent assembly issues caused by haplotype variation but this resulted in a composite of the two genomes. Here we report a haplotype-aware scaffolding and polishing pipeline which was used to create haplotype-resolved, chromosome-level genome assemblies of Angus (taurine) and Brahman (indicine) cattle subspecies from contigs generated by the trio binning method. These assemblies reveal structural and copy number variants that differentiate the subspecies and that variant detection is sensitive to the specific reference genome chosen. Six genes with immune related functions have additional copies in the indicine compared with taurine lineage and an indicus-specific extra copy of fatty acid desaturase is under positive selection. The haplotyped genomes also enable transcripts to be phased to detect allele-specific expression. This work exemplifies the value of haplotype-resolved genomes to better explore evolutionary and functional variations.
被引量:55 发表:1970
-
Assembly of chromosome-scale contigs by efficiently resolving repetitive sequences with long reads.
The abundant repetitive sequences in complex eukaryotic genomes cause fragmented assemblies, which lose value as reference genomes, often due to incomplete gene sequences and unanchored or mispositioned contigs on chromosomes. Here we report a genome assembly method HERA, which resolves repeats efficiently by constructing a connection graph from an overlap graph. We test HERA on the genomes of rice, maize, human, and Tartary buckwheat with single-molecule sequencing and mapping data. HERA correctly assembles most of the previously unassembled regions, resulting in dramatically improved, highly contiguous genome assemblies with newly assembled gene sequences. For example, the maize contig N50 size reaches 61.2 Mb and the Tartary buckwheat genome comprises only 20 contigs. HERA can also be used to fill gaps and fix errors in reference genomes. The application of HERA will greatly improve the quality of new or existing assemblies of complex genomes.
被引量:35 发表:1970