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Published by Thomson Current Drugs. ISSN: 1464-8431.<br /><br />Current Opinion in Molecular Therapeutics is designed to give you an overview of the most important developments across this field of research and saves you from having to hunt through the proliferation of scientific literature. Throughout the course of a year the journal highlights relevant progress made in gene therapy, vaccines, oligonucleotides, gene delivery systems, vectors, genomics and proteomics.
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Near-infrared-emitting semiconductor quantum dots for tumor imaging and targeting.
被引量：5 发表：2010
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Novel immunotherapeutic approaches to glioma.
被引量：8 发表：2006
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Therapeutic recombinant proteins: trends in US approvals 1982 to 2002.
被引量：3 发表：2003
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Therapeutic monoclonal antibodies: trends in development and approval in the US.
被引量：- 发表：2002
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Alphavirus-based vaccines.
Alphavirus vectors can be appliedfor vaccine production as naked RNA molecules, DNA plasmids or recombinant replication-deficient viral particles. The common feature for all these vectors is the alphavirus replicon, which is responsible for the strong RNA amplification in host cells enabling extreme transgene expression levels. Additionally, live replication-proficient virus has elicited reasonable immune responses. For many viral genes, humoral and cellular cytotoxic T-lymphocyte responses have been obtained. In other cases, monoclonal antibodies have been generated against the encoded antigen. Moreover, protection against challenges with lethal doses of virus has been achieved. Alphavirus vaccine applications have been further extended to models for prophylactic tumor therapy.
被引量：- 发表：2002
