自引率: 8.3%
被引量: 5502
通过率: 暂无数据
审稿周期: 1
版面费用: 暂无数据
国人发稿量: 11
投稿须知/期刊简介:
Published by Elsevier Science. ISSN: 1438-4639.<br /><br />The journal serves as a multidisciplinary forum for all research areas of hygiene, toxicology and environmental and occupational health. Original papers, rapid communications, reviews, case reports, technical notes, and editorials are invited and will be accepted for publication following peer review. High priority will be given to articles on environmental toxicology, risk assessment, susceptible populations, interactive effects of biological, physical and chemical factors, public health, environmental epidemiology, hospital hygiene, environmental microbiology, and clinical aspects related to environmental and occupational medicine.
期刊描述简介:
Published by Elsevier Science. ISSN: 1438-4639. The journal serves as a multidisciplinary forum for all research areas of hygiene, toxicology and environmental and occupational health. Original papers, rapid communications, reviews, case reports, technical notes, and editorials are invited and will be accepted for publication following peer review. High priority will be given to articles on environmental toxicology, risk assessment, susceptible populations, interactive effects of biological, physical and chemical factors, public health, environmental epidemiology, hospital hygiene, environmental microbiology, and clinical aspects related to environmental and occupational medicine.
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Biodegradation of trimethoprim and sulfamethoxazole in secondary effluent by microalgae-bacteria consortium.
Trimethoprim (TMP) and sulfamethoxazole (SMX) are bacteriostatic agents, which are co-administered to patients during infection treatment due to their synergetic effects. Once consumed, TMP and SMX end up in wastewater and are directed to municipal wastewater treatment plants (WWTPs) which fail to remove these contaminants from municipal wastewater. The discharge of WWTP effluents containing antibiotics in the environment is a major concern for public health as it contributes to the spread of antimicrobial resistance. Improving treatment applied in WWTPs is one of the measures to tackle this issue. In this study, a natural microalgae-bacteria consortium cultivated under low intensity LED irradiation was used as a quaternary treatment to assess the removal of TMP alone (50 μg L-1) and also mixed with SMX (TMP/SMX; 50 μg L-1 of each) from real WWTP secondary effluents from anaerobic treatment systems. The removal of the sulfonamide resistance gene, sul1, was also evaluated. This is the first study assessed the removal of TMP alone and TMP associated with SMX in real effluent using microalgae-bacteria consortium without nutrient enrichment. Biodegradation experiments were conducted for 7 days, residual amount of antibiotics were assessed by low-temperature partitioning extraction (LTPE) followed by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS) and sul1 was analyzed by quantitative Polymerase Chain Reaction (qPCR). Results showed that SMX removal (48.34%) was higher than TMP (24.58%) in the mixture. The presence of both antibiotics at 50 μg L-1 did not inhibit microalgae-bacteria consortium growth. After 7 days, there was a slight increase in the absolute abundance of sul1 and 16S rRNA. The main removal mechanism for both antibiotics might be attributed to symbiotic biodegradation as bioadsorption, bioaccumulation and abiotic factors were very low or insignificant. While the application of a microalgae-bacteria consortium as a quaternary treatment seems to be a promising alternative, further research to improve degradation rate aiming at a global removal >80% as required in the Swiss and European directives is encouraged.
被引量：- 发表：1970
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The SAM-Krom biomonitoring study shows occupational exposure to hexavalent chromium and increased genotoxicity in Denmark.
被引量：- 发表：1970
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Long-term exposure to green and blue space and incidence of cardiovascular disease: A Danish Nurse Cohort study.
被引量：- 发表：1970
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Multiple mycotoxin exposure assessment through human biomonitoring in an esophageal cancer case-control study in the Arsi-Bale districts of Oromia region of Ethiopia.
被引量：1 发表：1970
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Aging of drinking water transmission pipes during long-term operation as a potential source of nano- and microplastics.
被引量：- 发表：1970
