Tumour necrosis factor-alpha in conjunctivae affected by ocular cicatricial pemphigoid.

被引量：4 发表：1970

Correlation between optic disc topography and retinal nerve fibre layer measurements in glaucoma.

被引量：2 发表：2005

Histology of microcornea complicated by bullous keratopathy.

PURPOSE:To report a child with a microcornea complicated by bullous keratopathy and to present the results of a developmental and histological investigation of a microcornea. METHODS:Clinical and histopathological examination. RESULTS:Histopathological examination of the microcornea showed that the microcornea of our case lacked the non-banded zone of Descemet's layer and formed collagenous layer and secondary Descemet's membrane. CONCLUSION:This case demonstrates that histological finding of microcornea is not necessarily normal.

被引量：1 发表：2001

Effect of localized defocus on detection thresholds for different sized targets in the fovea and periphery.

PURPOSE:Previous studies of optical blur in perimetry have measured the effect of foveal refractive error on peripheral perimetric detection thresholds. Since peripheral refractive error can be significantly different from that of the fovea we wished to remove the ambiguity of previous results by correcting the actual peripheral refractive error first before adding blur. METHODS:We measured detection thresholds in the fovea and at 30 degrees in the horizontal temporal field in two trained observers. Peripheral refractive error was determined at each location and thresholds measured at the same locations for stimuli ranging in size from 0.2 to 6.4 degrees and refractive errors between +/-4.00 diopters. RESULTS:Foveal thresholds increased immediately with increasing refractive error, particularly for smaller stimulus sizes. At 30 degrees, thresholds for smaller stimuli were less affected by defocus initially and then increased more sharply. Larger stimuli were relatively unaffected by defocus such that when stimulus size reached 1.6 degrees there was little or no increase in threshold for refractive error between +/-4.00 diopters. CONCLUSIONS:Peripheral refractive error, largely forgotten by perimetrists, has a significant effect on performance, particularly for smaller stimuli. Differences in foveal vs peripheral viewing can be explained by differences in ganglion cell receptive field sizes.

被引量：11 发表：2001

Transpupillary thermotherapy as an adjunct to ruthenium plaque radiotherapy for choroidal melanoma.

PURPOSE:To review the Swedish experience using transpupillary thermotherapy (TTT) as an adjunct to ruthenium plaque radiotherapy for choroidal melanoma. METHODS:A retrospective chart review of 27 patients receiving TTT for juxtapapillary or juxtafoveal growth present at the time of diagnosis, or recurrent growth at the tumour margin, or significant exudation following ruthenium brachytherapy for choroidal melanoma. RESULTS:Follow-up ranged from 6 to 29 months (median=20 months). Tumour growth regressed completely (n=8), regressed partially (n=11), remain unchanged (n=6) or progressed (n=2). Complications included focal lens opacity with or without associated posterior synechiae (n=3), retinal haemorrhage (n=2) and retinal vein occlusion (n=1). Seventeen patients (63%) maintained or improved visual acuity and 2 eyes were enucleated following combined treatment. CONCLUSION:Many of the treated eyes would have been enucleated in the past, suggesting that TTT used in combination with ruthenium brachytherapy improves the short term globe salvage rate. Ocular side effects do occur but are usually not significant.

被引量：6 发表：2001