自引率: 1.4%
被引量: 16037
通过率: 暂无数据
审稿周期: 2.2
版面费用: 暂无数据
国人发稿量: 98
投稿须知/期刊简介:
Published by Elsevier Science. ISSN: 1357-2725.<br /><br />The International Journal of Biochemistry & Cell Biology publishes papers containing the results of original research in all areas of contemporary biochemistry. This includes biochemical studies employing techniques of cell and molecular biology and all areas of biomedical research. The journal also contains a regular series of up-to-the-minute reviews highlighting major developments in modern biochemistry written by internationally renowned experts in the field. Because of the breadth of subjects covered by the journal, the aim and significance of every study should be made clear to readers who are not expert in the subject of the paper. New to the journal is a section entitled 'Molecules in Focus' which each month will publish an article focusing on a topical molecule and highlighting its potential industrial and/or pharmaceutical applications.
期刊描述简介:
IJBCB publishes original research articles, invited reviews and in-focus articles in all areas of cell and molecular biology and biomedical research. Topics of interest include, but are not limited to: Mechanistic studies of cells, cell organelles, sub-cellular molecular pathways and metabolism Novel insights into disease pathogenesis Nanotechnology with implication to biological and medical processes Genomics and bioinformatics
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PIAS1 S510G variant acts as a genetic modifier of spinocerebellar ataxia type 3 by selectively impairing mutant ataxin-3 proteostasis.
被引量：- 发表：1970
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Unveiling the role of taurine and SLC6A6 in tumor immune evasion: Implications for gastric cancer therapy.
被引量：- 发表：1970
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Microtubules and cardiovascular diseases: insights into pathology and therapeutic strategies.
Microtubules, complex cytoskeletal structures composed of tubulin proteins in eukaryotic cells, have garnered recent attention in cardiovascular research. Investigations have focused on the post-translational modifications of tubulin, including acetylation and detyrosination. Perturbations in microtubule homeostasis have been implicated in various pathological processes associated with cardiovascular diseases such as heart failure, ischemic heart disease, and arrhythmias. Thus, elucidating the intricate interplay between microtubule dynamics and cardiovascular pathophysiology is imperative for advancing preventive and therapeutic strategies. Several natural compounds have been identified to potentially modulate microtubules, thereby exerting regulatory effects on cardiovascular diseases. This review synthesizes current literature to delineate the roles of microtubules in cardiovascular diseases and assesses the potential of natural compounds in microtubule-targeted therapies.
被引量：- 发表：1970
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The use of serotonin type 7 receptor antagonists as a pharmacological intervention in chronic stress. Insights from animal studies.
This mini-review presents our current understanding of serotonin type 7 receptor research focusing on the possible network mechanisms underlying the behavioral action of receptor antagonists. The serotonin type 7 receptor is expressed widely throughout the nervous system and known to be involved in various cognitive and physiological mechanisms. It became a clinically significant target after the discovery that its selective antagonist SB 269970 can exert rapid-onset antidepressant effects either alone or in combination with lower doses of conventional antidepressant drugs. Further research has shown that administration of SB 269970 can effectively counteract negative neurobiological outcomes in various chronic stress paradigms. The authors hope they can introduce a wider scientific audience to this promising pharmacological target which, if successful, could in time lead to more discoveries and a better understanding of the underlying serotonin receptor biology as well as its clinical potential. HIGHLIGHTS.
被引量：- 发表：1970
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MEST promotes immune escape in gastric cancer by downregulating MHCI expression via SHP2.
被引量：- 发表：2024
