自引率: 4%
被引量: 5969
通过率: 暂无数据
审稿周期: 暂无数据
版面费用: 暂无数据
国人发稿量: 6
投稿须知/期刊简介:
Virchows Archiv is a medium for the publication of fundamental morphological research on disease in the widest sense and on human pathology in particular. Articles concerned with surgical pathology experimental morphology ultrastructural research immunocytochemical analysis and molecular biology may be accepted provided they illuminate some facet of human pathology. Consideration will be given to reports of work in other fields relevant to the understanding of human pathology. Papers on the application of new methods and techniques in pathology are also welcomed.
期刊描述简介:
Virchows Archiv is a medium for the publication of fundamental morphological research on disease in the widest sense and on human pathology in particular. Articles concerned with surgical pathology experimental morphology ultrastructural research immunocytochemical analysis and molecular biology may be accepted provided they illuminate some facet of human pathology. Consideration will be given to reports of work in other fields relevant to the understanding of human pathology. Papers on the application of new methods and techniques in pathology are also welcomed.
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Urologists and pathologists in prostate cancer screening.
被引量：- 发表：1970
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Aberrant localization of β1 integrin in podocyte cytoplasm of primary FSGS with cellular lesion.
被引量：- 发表：1970
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Oncocytic intraductal carcinoma of parotid gland with a novel AGK::BRAF gene fusion.
被引量：- 发表：1970
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Update on cutaneous mesenchymal tumors in the 5th edition of WHO classification of skin tumors with an emphasis on new fusion-associated neoplasms.
被引量：- 发表：1970
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Characterization of testicular embryonic-type neuroectodermal tumor and embryonic-type neuroectodermal tissue admixed with mature neuro-glial tissue using a broad immunohistochemical panel.
Embryonic-type neuroectodermal tumor (ENT) is a somatic-type malignancy characterized by overgrowth of embryonic-type neuroectodermal tissue (EtNT). In germ cell tumors, EtNT is frequently intermingled with other components that may exhibit significant morphologic overlap [mature neuro-glial tissue (MNGT), nephroblastomatous tissues, and primitive endodermal-type glands]. Therefore, the quantification of EtNT (crucial for the diagnosis of ENT) can be challenging. In this study, we investigated the immunohistochemical profile of ENT, EtNT, and MNGT using a broad immunohistochemical panel. We found that SOX2 was the most sensitive marker for EtNT (100%), but it also stained MNGT (28.6%). GFAP and S100 were relatively sensitive (71.4%) and highly specific (GFAP 100%, S100 85.8%) for MNGT, whereas synaptophysin stained both. Combining our results with those of previous studies, we propose that a combination of SOX11, SOX2, GFAP, S100, AFP, villin, CDX2, PAX8, and nuclear WT1 may help to identify and quantify EtNT in germ cell tumors.
被引量：- 发表：1970
