自引率: 0.8%
被引量: 5119
通过率: 暂无数据
审稿周期: 1.83
版面费用: 暂无数据
国人发稿量: 12
投稿须知/期刊简介:
Research in Microbiology publishes original reports covering all aspects of microbiology, including general and molecular microbiology, physiology and microbial genetics, environmental and applied microbiology, industrial microbiology, mycology and medical microbiology. In addition to full-length articles, brief notes as well as position papers are welcome. This international journal also provides Forums for the exchange of ideas and opinions and a column entitles ''Times and Trends''. The overriding criteria for publication are originality, high scientific quality and up-to-date relevance. Papers should be written with a wide audience of microbiologists in mind.
期刊描述简介:
Originally founded as the "Annales de l'Institut Pasteur", Research in Microbiology has been a leading source of up-to-date information in the field of microbiology for more than a century. It publishes papers based on original research in fundamental and applied biology of bacteria, archaea and lower eukaryotes. It covers all aspects of the microbial taxonomy, phylogeny, ecology, physiology and metabolism, molecular genetics and genomics, as well as the interactions between microbes and interactions of microbes with their environment. Research in Microbiology currently publishes 10 issues a year, including an annual Forum issue, original articles, reviews, and letters to the Editor.
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Lipid lysination by MprF contributes to hemolytic pigment retention in group B Streptococcus.
Group B Streptococcus (GBS) is the leading cause of neonatal sepsis and meningitis. A major virulence factor is a pigmented beta-haemolytic/cyto-lysin (β-h/c) toxin with an ornithine rhamnolipid structure. We initially observed that absence of MprF enzyme altered pigmentation and haemolytic activity in GBS. Next, we showed that MprF-dependent lipid lysination contributes to the retention of the ornithine rhamnolipid within GBS membrane. Furthermore, cationic lipidation by MprF altered membrane properties contributing to resistance to the cyclic lipopeptide daptomycin and to acidic pH. This study highlights the importance of cationic lipids in cell envelope homeostasis and in modulating β-h/c activity.
被引量：- 发表：1970
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Effect of gamma irradiation on the proteogenome of cold-acclimated Kocuria rhizophila PT10.
The effects of ionizing radiation (IR) on the protein dynamics of cold-stressed cells of a radioresistant actinobacterium, Kocuria rhizophila PT10, isolated from the rhizosphere of the desert plant Panicum turgidum were investigated using a shotgun methodology based on nanoflow liquid chromatography coupled to tandem mass spectrometry. Overall, 1487 proteins were certified, and their abundances were compared between the irradiated condition and control. IR of cold-acclimated PT10 triggered the over-abundance of proteins involved in (1) a strong transcriptional regulation, (2) amidation of peptidoglycan and preservation of cell envelope integrity, (3) detoxification of reactive electrophiles and regulation of the redox status of proteins, (4) base excision repair and prevention of mutagenesis and (5) the tricarboxylic acid (TCA) cycle and production of fatty acids. Also, one of the more significant findings to emerge from this study is the SOS response of stressed PT10. Moreover, a comparison of top hits radio-modulated proteins of cold-acclimated PT10 with proteomics data from gamma-irradiated Deinococcus deserti showed that stressed PT10 has a specific response characterised by a high over-abundance of NemA, GatD, and UdgB.
被引量：- 发表：1970
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Endopeptidase activities of Clostridium botulinum toxins in the development of this bacterium.
By-products like CO₂ and organic acids, produced during Clostridium botulinum growth, appear to inhibit its development and reduce ATP production. A decrease in ATP production creates an imbalance in the ATP/GTP ratio. GTP activates CodY, which regulates BoNT expression. This toxin is released into the extracellular medium. Its light chains act as a specific endopeptidase, targeting SNARE proteins. The specific amino acids released enter the cells and are metabolized by the Stickland reaction, resulting in the synthesis of ATP. This ATP might then be used by histidine kinases to activate Spo0A, the main regulator initiating sporulation, through phosphorylation.
被引量：- 发表：1970
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Molecular insights into PGPR fluorescent Pseudomonads complex mediated intercellular and interkingdom signal transduction mechanisms in promoting plant's immunity.
The growth-promoting and immune modulatory properties of different strains of plant growth promoting rhizobacteria (PGPR) fluorescent Pseudomonads complex (PFPC) can be explored to combat food security challenges. These PFPC prime plants through induced systemic resistance, fortify plants to overcome future pathogen-mediated vulnerability by eliciting robust systemic acquired resistance through regulation by nonexpressor of pathogenesis-related genes 1. Moreover, outer membrane vesicles released from Pseudomonas fluorescens also elicit a broad spectrum of immune responses, presenting a rapid viable alternative to whole cells. Thus, PFPC can help the host to maintain an equilibrium between growth and immunity, ultimately leads to increased crop yield.
被引量：- 发表：1970
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Metagenomics approaches in unveiling the dynamics of Plant Growth-Promoting Microorganisms (PGPM) vis-à-vis Phytophthora sp. suppression in various crop ecological systems.
Phytophthora species are destructive pathogens causing yield losses in different ecological systems, such as potato, black pepper, pepper, avocado, citrus, and tobacco. The diversity of plant growth-promoting microorganisms (PGPM) plays a crucial role in disease suppression. Knowledge of metagenomics approaches is essential for assessing the dynamics of PGPM and Phytophthora species across various ecosystems, facilitating effective management strategies for better crop protection. This review discusses the dynamic interplay between PGPM and Phytophthora sp. using metagenomics approaches that sheds light on the potential of PGPM strains tailored to specific crop ecosystems to bolster pathogen suppressiveness.
被引量：- 发表：1970
