自引率: 5.7%
被引量: 6607
通过率: 暂无数据
审稿周期: 3.5
版面费用: 暂无数据
国人发稿量: 19
投稿须知/期刊简介:
Epilepsy Research provides for rapid publication of high quality articles in both experimental and clinical epileptology, where the principal emphasis of the research is concerned with brain mechanisms in epilepsy. It is intended to provide a forum for the many disciplines involved such as neurology, neurosurgery, neurophysiology, neuropharmacology, neurochemistry, neuroanatomy, neuropathology, neuroendocrinology, neurotoxicology, neurogenetics, neuroimaging, neuropsychology, neuropsychiatry, molecular neurobiology, clinical chemistry and paediatrics. As such the journal will publish original papers from any of these individual areas or studies of a multidisciplinary nature. Clinical and experimental research papers adopting fresh conceptual approaches to the study of epilepsy are encouraged. The overriding criteria for publication are novelty, significant clinical or experimental relevance, and interest to a multidisciplinary audience.
期刊描述简介:
Epilepsy Research provides for rapid publication of high quality articles in both experimental and clinical epileptology, where the principal emphasis of the research is concerned with brain mechanisms in epilepsy. It is intended to provide a forum for the many disciplines involved such as neurology, neurosurgery, neurophysiology, neuropharmacology, neurochemistry, neuroanatomy, neuropathology, neuroendocrinology, neurotoxicology, neurogenetics, neuroimaging, neuropsychology, neuropsychiatry, molecular neurobiology, clinical chemistry and paediatrics. As such the journal will publish original papers from any of these individual areas or studies of a multidisciplinary nature. Clinical and experimental research papers adopting fresh conceptual approaches to the study of epilepsy are encouraged. The overriding criteria for publication are novelty, significant clinical or experimental relevance, and interest to a multidisciplinary audience.
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Psychosis and schizophrenia among patients with epilepsy: A systematic review and meta-analysis.
被引量：- 发表：1970
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The relationship between perceived stress, spiritual well-being and alexithymia in people with epilepsy: A path analysis.
被引量：- 发表：1970
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Extracting seizure control metrics from clinic notes of patients with epilepsy: A natural language processing approach.
被引量：- 发表：1970
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A side-by-side comparison of fine-tuning options for treatment of medically refractory epilepsy: Antiseizure medications, vagus nerve stimulation and ketogenic diet therapies.
There are many treatment options available for patients with medically refractory epilepsy including antiseizure medications, surgery, devices and ketogenic diet therapy. Ketogenic diet therapy has been shown to be a safe and effective treatment option in adult and pediatric patients. In order to obtain maximal clinical effectiveness and tolerability of any treatment option, adjustments are often necessary. This article outlines the "fine-tuning" options available for antiseizure medications, vagus nerve stimulation and ketogenic diet therapies and demonstrates that ketogenic diet therapies offer a wider array of personalizing and fine-tuning options.
被引量：- 发表：1970
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NS-Pten knockout mice exhibit sex and hippocampal subregion-specific increases in microglia/macrophage density.
Seizures induce hippocampal subregion dependent enhancements in microglia/macrophage phagocytosis and cytokine release that may contribute to the development of epilepsy. As a model of hyperactive mTOR induced epilepsy, neuronal subset specific phosphatase and tensin homolog (NS-Pten) knockout (KO) mice exhibit hyperactive mTOR signaling in the hippocampus, seizures that progress with age, and enhanced hippocampal microglia/macrophage activation. However, it is unknown where microglia/macrophages are most active within the hippocampus of NS-Pten KO mice. We quantified the density of IBA1 positive microglia/macrophages in the CA1, CA2/3, and dentate gyrus of NS-Pten KO and wildtype (WT) male and female mice at 4, 10, and 15 weeks of age. NS-Pten KO mice exhibited an overall increase in the number of IBA1 positive microglia/macrophages in each subregion and in the entire hippocampus. After accounting for differences in size, the whole hippocampus of NS-Pten KO mice still exhibited an increased density of IBA1 positive microglia/macrophages. Subregion analyses showed that this increase was restricted to the dentate gyrus of both male and female NS-Pten KO mice and to the CA1 of male NS-Pten KO mice. These data suggest enhanced microglia/macrophage activity may occur in the NS-Pten KO mice in a hippocampal subregion and sex-dependent manner. Future work should seek to determine whether these region-specific increases in microgliosis play a role in the progression of epilepsy in this model.
被引量：- 发表：1970
